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- NCIT_C29395 IAO_0000115 "A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)" @default.
- NCIT_C29395 NCIT_A32 NCIT_C1909 @default.
- NCIT_C29395 NCIT_NHC0 "C29395" @default.
- NCIT_C29395 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29395 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29395 NCIT_P108 "Pyrazinamide" @default.
- NCIT_C29395 NCIT_P175 "14911" @default.
- NCIT_C29395 NCIT_P207 "C0034239" @default.
- NCIT_C29395 NCIT_P210 "98-96-4" @default.
- NCIT_C29395 NCIT_P319 "2KNI5N06TI" @default.
- NCIT_C29395 NCIT_P322 "FDA" @default.
- NCIT_C29395 NCIT_P322 "GDC" @default.
- NCIT_C29395 NCIT_P329 "701809" @default.
- NCIT_C29395 NCIT_P330 "701809" @default.
- NCIT_C29395 NCIT_P350 "C5H5N3O" @default.
- NCIT_C29395 NCIT_P366 "Pyrazinamide" @default.
- NCIT_C29395 NCIT_P368 "CHEBI:45285" @default.
- NCIT_C29395 NCIT_P375 "Pyrazinamide" @default.
- NCIT_C29395 NCIT_P399 "701809" @default.
- NCIT_C29395 normalizedInformationContent "100" @default.
- NCIT_C29395 referenceCount "1" @default.
- NCIT_C29395 hasExactSynonym "PYRAZINAMIDE" @default.
- NCIT_C29395 hasExactSynonym "Pyrazinamide" @default.
- NCIT_C29395 inSubset NCIT_C157711 @default.
- NCIT_C29395 inSubset NCIT_C157712 @default.
- NCIT_C29395 inSubset NCIT_C176424 @default.
- NCIT_C29395 inSubset NCIT_C177537 @default.
- NCIT_C29395 inSubset NCIT_C63923 @default.
- NCIT_C29395 type Class @default.
- NCIT_C29395 isDefinedBy ncit.owl @default.
- NCIT_C29395 label "Pyrazinamide" @default.
- NCIT_C29395 subClassOf NCIT_C1908 @default.
- NCIT_C29395 subClassOf NCIT_C1909 @default.
- NCIT_C29395 subClassOf NCIT_C254 @default.
- NCIT_C29395 subClassOf NCIT_C280 @default.
- NCIT_C29395 subClassOf NCIT_C29395 @default.
- NCIT_C29395 subClassOf NCIT_C52588 @default.