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- NCIT_C29416 IAO_0000115 "A benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions. In addition, risperidone has low to moderate affinity for histamine H1, 5-HT1A, 5-HT1C, and 5-HT1D receptors, while it has weak affinity for dopamine D1 and haloperidol-sensitive sigma site receptors." @default.
- NCIT_C29416 NCIT_NHC0 "C29416" @default.
- NCIT_C29416 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29416 NCIT_P108 "Risperidone" @default.
- NCIT_C29416 NCIT_P207 "C0073393" @default.
- NCIT_C29416 NCIT_P210 "106266-06-2" @default.
- NCIT_C29416 NCIT_P319 "L6UH7ZF8HC" @default.
- NCIT_C29416 NCIT_P322 "FDA" @default.
- NCIT_C29416 NCIT_P350 "C23H27FN4O2" @default.
- NCIT_C29416 NCIT_P366 "Risperidone" @default.
- NCIT_C29416 NCIT_P368 "CHEBI:8871" @default.
- NCIT_C29416 NCIT_R122 NCIT_C16484 @default.
- NCIT_C29416 NCIT_R122 NCIT_C16486 @default.
- NCIT_C29416 NCIT_R122 NCIT_C16554 @default.
- NCIT_C29416 NCIT_R122 NCIT_C16865 @default.
- NCIT_C29416 NCIT_R122 NCIT_C16946 @default.
- NCIT_C29416 NCIT_R122 NCIT_C17021 @default.
- NCIT_C29416 NCIT_R122 NCIT_C17287 @default.
- NCIT_C29416 NCIT_R122 NCIT_C20027 @default.
- NCIT_C29416 NCIT_R122 NCIT_C26548 @default.
- NCIT_C29416 NCIT_R122 NCIT_C28459 @default.
- NCIT_C29416 normalizedInformationContent "100" @default.
- NCIT_C29416 referenceCount "1" @default.
- NCIT_C29416 hasExactSynonym "RISPERIDONE" @default.
- NCIT_C29416 hasExactSynonym "Risperidone" @default.
- NCIT_C29416 inSubset NCIT_C63923 @default.
- NCIT_C29416 type Class @default.
- NCIT_C29416 isDefinedBy ncit.owl @default.
- NCIT_C29416 label "Risperidone" @default.
- NCIT_C29416 subClassOf B491893912024d334840882877875d860 @default.
- NCIT_C29416 subClassOf Bfcb6bc8b559746f13c7de645803d3c66 @default.
- NCIT_C29416 subClassOf NCIT_C1908 @default.
- NCIT_C29416 subClassOf NCIT_C1909 @default.
- NCIT_C29416 subClassOf NCIT_C29416 @default.
- NCIT_C29416 subClassOf NCIT_C29710 @default.
- NCIT_C29416 subClassOf NCIT_C78272 @default.