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- NCIT_C29478 IAO_0000115 "A preparation of lymphocytes harvested from a patient and genetically modified ex vivo for use in gene therapy for the patient's cancer. Ex vivo, the lymphocytes are transduced with the N2 retroviral vector, which is modified to express a gene whose protein product either kills tumor cells or elicits specific anti-tumor immunity. Genetically modified lymphocytes are infused back into the patient from whom they were harvested, locate to the tumor site, and express the candidate protein that kills tumor cells or stimulates host anti-tumor immunity. (NCI04)" @default.
- NCIT_C29478 NCIT_NHC0 "C29478" @default.
- NCIT_C29478 NCIT_P106 "Cell" @default.
- NCIT_C29478 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29478 NCIT_P108 "Tumor Infiltrating Lymphocytes-N2-Transduced" @default.
- NCIT_C29478 NCIT_P207 "C1519682" @default.
- NCIT_C29478 NCIT_P366 "Tumor_Infiltrating_Lymphocytes-N2-Transduced" @default.
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- NCIT_C29478 normalizedInformationContent "100" @default.
- NCIT_C29478 referenceCount "1" @default.
- NCIT_C29478 hasExactSynonym "Tumor Infiltrating Lymphocytes-N2-Transduced" @default.
- NCIT_C29478 inSubset NCIT_C128784 @default.
- NCIT_C29478 type Class @default.
- NCIT_C29478 isDefinedBy ncit.owl @default.
- NCIT_C29478 label "Tumor Infiltrating Lymphocytes-N2-Transduced" @default.
- NCIT_C29478 subClassOf B28136adf3308b443d1fc286da3e1cfce @default.
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- NCIT_C29478 subClassOf NCIT_C308 @default.