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- NCIT_C29491 IAO_0000115 "The hydrochloride salt form of terazosin, a quinazoline derivative with adrenergic antagonistic property. Terazosin hydrochloride selectively inhibits alpha-1 adrenergic receptors, resulting in vasodilation leading to decreased peripheral vascular resistance and a reduced venous return to the heart as well as decreased urethral resistance, which potentially improving urine flow and symptoms related to benign prostatic hyperplasia. In addition, terazosin decreases low-density lipoproteins (LDL) and triglycerides while increasing the concentration of high-density lipoproteins (HDL)." @default.
- NCIT_C29491 NCIT_A6 NCIT_C61964 @default.
- NCIT_C29491 NCIT_NHC0 "C29491" @default.
- NCIT_C29491 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29491 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29491 NCIT_P108 "Terazosin Hydrochloride" @default.
- NCIT_C29491 NCIT_P207 "C0770137" @default.
- NCIT_C29491 NCIT_P210 "70024-40-7" @default.
- NCIT_C29491 NCIT_P319 "D32S14F082" @default.
- NCIT_C29491 NCIT_P322 "FDA" @default.
- NCIT_C29491 NCIT_P325 "A drug used to treat urinary problems caused by an enlarged prostate. It is also used to treat high blood pressure and is being studied in the treatment of other conditions. Terazosin hydrochloride relaxes muscle tissue in blood vessels and in the prostate. It is a type of alpha blocker." @default.
- NCIT_C29491 NCIT_P350 "C19H25N5O4.HCl.2H2O" @default.
- NCIT_C29491 NCIT_P366 "Terazosin_Hydrochloride" @default.
- NCIT_C29491 NCIT_P368 "CHEBI:9446" @default.
- NCIT_C29491 normalizedInformationContent "100" @default.
- NCIT_C29491 referenceCount "1" @default.
- NCIT_C29491 hasExactSynonym "Hytrin" @default.
- NCIT_C29491 hasExactSynonym "TERAZOSIN HYDROCHLORIDE" @default.
- NCIT_C29491 hasExactSynonym "Terazosin Hydrochloride Dihydrate" @default.
- NCIT_C29491 hasExactSynonym "Terazosin Hydrochloride" @default.
- NCIT_C29491 hasExactSynonym "terazosin hydrochloride" @default.
- NCIT_C29491 inSubset NCIT_C63923 @default.
- NCIT_C29491 type Class @default.
- NCIT_C29491 isDefinedBy ncit.owl @default.
- NCIT_C29491 label "Terazosin Hydrochloride" @default.
- NCIT_C29491 subClassOf NCIT_C1908 @default.
- NCIT_C29491 subClassOf NCIT_C1909 @default.
- NCIT_C29491 subClassOf NCIT_C29491 @default.
- NCIT_C29491 subClassOf NCIT_C29713 @default.
- NCIT_C29491 subClassOf NCIT_C29747 @default.
- NCIT_C29491 subClassOf NCIT_C72900 @default.
- NCIT_C29491 subClassOf NCIT_C78272 @default.