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- NCIT_C29497 IAO_0000115 "The maleate salt form of triethylperazine, a piperazine phenothiazine derivative and a dopamine antagonist used as antiemetic. Thiethylperazine blocks postsynaptic dopamine 2 (D2) receptors in the medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain. Peripherally, thiethylperazine blocks the vagus nerve in the gastrointestinal tract. In addition, this agent also shows antagonistic activities mediated through muscarinic receptors, H1-receptors, and alpha(1)-receptors." @default.
- NCIT_C29497 NCIT_A6 NCIT_C62081 @default.
- NCIT_C29497 NCIT_NHC0 "C29497" @default.
- NCIT_C29497 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29497 NCIT_P108 "Thiethylperazine Maleate" @default.
- NCIT_C29497 NCIT_P175 "130044" @default.
- NCIT_C29497 NCIT_P207 "C0723786" @default.
- NCIT_C29497 NCIT_P210 "1179-69-7" @default.
- NCIT_C29497 NCIT_P319 "RUK64CF26E" @default.
- NCIT_C29497 NCIT_P322 "FDA" @default.
- NCIT_C29497 NCIT_P350 "C22H29N3S2.2C4H4O4" @default.
- NCIT_C29497 NCIT_P366 "Thiethylperazine" @default.
- NCIT_C29497 NCIT_P368 "CHEBI:32216" @default.
- NCIT_C29497 normalizedInformationContent "100" @default.
- NCIT_C29497 referenceCount "1" @default.
- NCIT_C29497 hasExactSynonym "10H-Phenothiazine, 2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate" @default.
- NCIT_C29497 hasExactSynonym "GS-95" @default.
- NCIT_C29497 hasExactSynonym "Norzine" @default.
- NCIT_C29497 hasExactSynonym "THIETHYLPERAZINE MALEATE" @default.
- NCIT_C29497 hasExactSynonym "Thiethylperazine Maleate" @default.
- NCIT_C29497 hasExactSynonym "Torecan" @default.
- NCIT_C29497 inSubset NCIT_C63923 @default.
- NCIT_C29497 type Class @default.
- NCIT_C29497 isDefinedBy ncit.owl @default.
- NCIT_C29497 label "Thiethylperazine Maleate" @default.
- NCIT_C29497 subClassOf NCIT_C1908 @default.
- NCIT_C29497 subClassOf NCIT_C1909 @default.
- NCIT_C29497 subClassOf NCIT_C267 @default.
- NCIT_C29497 subClassOf NCIT_C29497 @default.
- NCIT_C29497 subClassOf NCIT_C78272 @default.