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- NCIT_C295 IAO_0000115 "A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth." @default.
- NCIT_C295 NCIT_A5 NCIT_C28857 @default.
- NCIT_C295 NCIT_NHC0 "C295" @default.
- NCIT_C295 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C295 NCIT_P106 "Antibiotic" @default.
- NCIT_C295 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C295 NCIT_P108 "Bacitracin" @default.
- NCIT_C295 NCIT_P175 "45737" @default.
- NCIT_C295 NCIT_P207 "C0004599" @default.
- NCIT_C295 NCIT_P210 "1405-87-4" @default.
- NCIT_C295 NCIT_P319 "58H6RWO52I" @default.
- NCIT_C295 NCIT_P322 "FDA" @default.
- NCIT_C295 NCIT_P329 "42858" @default.
- NCIT_C295 NCIT_P330 "42858" @default.
- NCIT_C295 NCIT_P366 "Bacitracin" @default.
- NCIT_C295 NCIT_P368 "CHEBI:28669" @default.
- NCIT_C295 NCIT_P399 "42858" @default.
- NCIT_C295 normalizedInformationContent "88.143637090998837" @default.
- NCIT_C295 referenceCount "6" @default.
- NCIT_C295 hasExactSynonym "BACITRACIN" @default.
- NCIT_C295 hasExactSynonym "Bacitracin" @default.
- NCIT_C295 inSubset NCIT_C176424 @default.
- NCIT_C295 inSubset NCIT_C63923 @default.
- NCIT_C295 type Class @default.
- NCIT_C295 isDefinedBy ncit.owl @default.
- NCIT_C295 label "Bacitracin" @default.
- NCIT_C295 subClassOf NCIT_C1908 @default.
- NCIT_C295 subClassOf NCIT_C1909 @default.
- NCIT_C295 subClassOf NCIT_C254 @default.
- NCIT_C295 subClassOf NCIT_C258 @default.
- NCIT_C295 subClassOf NCIT_C295 @default.