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- NCIT_C29503 IAO_0000115 "An arylalkanoic acid and non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic activities. Although the exact mechanism through which tolmetin exerts its effects has yet to be fully elucidated, this agent appears to inhibit the enzyme prostaglandin synthase. This prevents the formation of prostaglandins from prostaglandin precursors, including the synthesis of the inflammatory prostaglandin E2 (PGE2) from the precursor prostaglandin H2 (PGH2). This prevents prostaglandin-mediated effects, including pain, inflammation and fever." @default.
- NCIT_C29503 NCIT_A5 NCIT_C61977 @default.
- NCIT_C29503 NCIT_NHC0 "C29503" @default.
- NCIT_C29503 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29503 NCIT_P108 "Tolmetin" @default.
- NCIT_C29503 NCIT_P207 "C0040377" @default.
- NCIT_C29503 NCIT_P210 "26171-23-3" @default.
- NCIT_C29503 NCIT_P319 "D8K2JPN18B" @default.
- NCIT_C29503 NCIT_P322 "FDA" @default.
- NCIT_C29503 NCIT_P350 "C15H15NO3" @default.
- NCIT_C29503 NCIT_P366 "Tolmetin" @default.
- NCIT_C29503 normalizedInformationContent "100" @default.
- NCIT_C29503 referenceCount "1" @default.
- NCIT_C29503 hasExactSynonym "TOLMETIN" @default.
- NCIT_C29503 hasExactSynonym "Tolmetin" @default.
- NCIT_C29503 inSubset NCIT_C63923 @default.
- NCIT_C29503 type Class @default.
- NCIT_C29503 isDefinedBy ncit.owl @default.
- NCIT_C29503 label "Tolmetin" @default.
- NCIT_C29503 subClassOf NCIT_C1908 @default.
- NCIT_C29503 subClassOf NCIT_C1909 @default.
- NCIT_C29503 subClassOf NCIT_C2198 @default.
- NCIT_C29503 subClassOf NCIT_C2356 @default.
- NCIT_C29503 subClassOf NCIT_C241 @default.
- NCIT_C29503 subClassOf NCIT_C257 @default.
- NCIT_C29503 subClassOf NCIT_C29503 @default.
- NCIT_C29503 subClassOf NCIT_C78272 @default.