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- NCIT_C29504 IAO_0000115 "The tartrate salt form of tolterodine, a benzhydryl compound and a muscarinic receptor antagonist possessing both antimuscarinic and antispasmodic properties. Both tolterodine and its active metabolite, 5-hydroxymethyltolterodine, competitively blocks muscarinic receptors, thereby inhibiting acetylcholine receptor binding. This antagonistic action results in an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, indicating an antimuscarinic action on the lower urinary tract.. The 5-hydroxymethyl metabolite appears to contribute significantly to the therapeutic effects." @default.
- NCIT_C29504 NCIT_A6 NCIT_C62083 @default.
- NCIT_C29504 NCIT_NHC0 "C29504" @default.
- NCIT_C29504 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29504 NCIT_P108 "Tolterodine Tartrate" @default.
- NCIT_C29504 NCIT_P207 "C0724710" @default.
- NCIT_C29504 NCIT_P210 "124937-52-6" @default.
- NCIT_C29504 NCIT_P319 "5T619TQR3R" @default.
- NCIT_C29504 NCIT_P322 "FDA" @default.
- NCIT_C29504 NCIT_P350 "C22H31NO.C4H6O6" @default.
- NCIT_C29504 NCIT_P366 "Tolterodine" @default.
- NCIT_C29504 NCIT_P368 "CHEBI:32245" @default.
- NCIT_C29504 normalizedInformationContent "100" @default.
- NCIT_C29504 referenceCount "1" @default.
- NCIT_C29504 hasExactSynonym "Detrol" @default.
- NCIT_C29504 hasExactSynonym "Detrusitol" @default.
- NCIT_C29504 hasExactSynonym "TOLTERODINE TARTRATE" @default.
- NCIT_C29504 hasExactSynonym "Tolterodine Tartrate" @default.
- NCIT_C29504 inSubset NCIT_C63923 @default.
- NCIT_C29504 type Class @default.
- NCIT_C29504 isDefinedBy ncit.owl @default.
- NCIT_C29504 label "Tolterodine Tartrate" @default.
- NCIT_C29504 subClassOf NCIT_C1908 @default.
- NCIT_C29504 subClassOf NCIT_C1909 @default.
- NCIT_C29504 subClassOf NCIT_C29504 @default.
- NCIT_C29504 subClassOf NCIT_C29704 @default.
- NCIT_C29504 subClassOf NCIT_C66880 @default.
- NCIT_C29504 subClassOf NCIT_C78272 @default.