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- NCIT_C29536 IAO_0000115 "A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. This agent's antitumor and antiangiogenesis activities may be related to the inhibition of histone deacetylases and nitric oxide synthase, which results in the inhibition of nitric oxide synthesis. (NCI04)" @default.
- NCIT_C29536 NCIT_A32 NCIT_C1909 @default.
- NCIT_C29536 NCIT_A5 NCIT_C48029 @default.
- NCIT_C29536 NCIT_A5 NCIT_C71156 @default.
- NCIT_C29536 NCIT_NHC0 "C29536" @default.
- NCIT_C29536 NCIT_P106 "Organic Chemical" @default.
- NCIT_C29536 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29536 NCIT_P107 "Valproic Acid" @default.
- NCIT_C29536 NCIT_P108 "Valproic Acid" @default.
- NCIT_C29536 NCIT_P175 "93819" @default.
- NCIT_C29536 NCIT_P207 "C0042291" @default.
- NCIT_C29536 NCIT_P210 "99-66-1" @default.
- NCIT_C29536 NCIT_P302 "Epilepsy; Mania; Migraine" @default.
- NCIT_C29536 NCIT_P319 "614OI1Z5WI" @default.
- NCIT_C29536 NCIT_P322 "CTRP" @default.
- NCIT_C29536 NCIT_P322 "FDA" @default.
- NCIT_C29536 NCIT_P322 "GDC" @default.
- NCIT_C29536 NCIT_P325 "A drug used to treat epileptic seizures and bipolar disorder and to prevent migraine headaches. It is also being studied in the treatment of several types of cancer. It blocks an enzyme that cells need to grow and may cause cancer cells to die. It also blocks the growth of new blood vessels that tumors need to grow. It is a type of anticonvulsant, histone deacetylase (HDAC) inhibitor, antimaniacal, migraine headache prophylactic, and antiangiogenesis agent." @default.
- NCIT_C29536 NCIT_P329 "350047" @default.
- NCIT_C29536 NCIT_P330 "350047" @default.
- NCIT_C29536 NCIT_P350 "C8H16O2" @default.
- NCIT_C29536 NCIT_P366 "Valproic_Acid" @default.
- NCIT_C29536 NCIT_P368 "CHEBI:39867" @default.
- NCIT_C29536 NCIT_P375 "Valproic Acid" @default.
- NCIT_C29536 NCIT_P399 "350047" @default.
- NCIT_C29536 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C29536 referenceCount "2" @default.
- NCIT_C29536 hasExactSynonym "2-Propylpentanoic Acid" @default.
- NCIT_C29536 hasExactSynonym "2-Propylvaleric Acid" @default.
- NCIT_C29536 hasExactSynonym "Depakene" @default.
- NCIT_C29536 hasExactSynonym "Di-n-propylacetic Acid" @default.
- NCIT_C29536 hasExactSynonym "Stavzor" @default.
- NCIT_C29536 hasExactSynonym "VALPROIC ACID" @default.
- NCIT_C29536 hasExactSynonym "Valproate" @default.
- NCIT_C29536 hasExactSynonym "Valproic Acid" @default.
- NCIT_C29536 hasExactSynonym "valproic acid" @default.
- NCIT_C29536 inSubset NCIT_C116977 @default.
- NCIT_C29536 inSubset NCIT_C116978 @default.
- NCIT_C29536 inSubset NCIT_C128784 @default.
- NCIT_C29536 inSubset NCIT_C157711 @default.
- NCIT_C29536 inSubset NCIT_C157712 @default.
- NCIT_C29536 inSubset NCIT_C176424 @default.
- NCIT_C29536 inSubset NCIT_C177537 @default.
- NCIT_C29536 inSubset NCIT_C63923 @default.
- NCIT_C29536 type Class @default.
- NCIT_C29536 isDefinedBy ncit.owl @default.
- NCIT_C29536 label "Valproic Acid" @default.
- NCIT_C29536 subClassOf NCIT_C1908 @default.
- NCIT_C29536 subClassOf NCIT_C1909 @default.
- NCIT_C29536 subClassOf NCIT_C264 @default.
- NCIT_C29536 subClassOf NCIT_C29536 @default.
- NCIT_C29536 subClassOf NCIT_C78272 @default.