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- NCIT_C29572 IAO_0000115 "Dr1-associated corepressor (205 aa, ~22 kDa) is encoded by the human DRAP1 gene. This protein is involved in the repression of gene expression." @default.
- NCIT_C29572 NCIT_NHC0 "C29572" @default.
- NCIT_C29572 NCIT_P100 "602289" @default.
- NCIT_C29572 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C29572 NCIT_P106 "Biologically Active Substance" @default.
- NCIT_C29572 NCIT_P108 "Dr1-Associated Corepressor" @default.
- NCIT_C29572 NCIT_P207 "C0388904" @default.
- NCIT_C29572 NCIT_P366 "DR1-Associated_Protein-1" @default.
- NCIT_C29572 NCIT_P93 "Q14919" @default.
- NCIT_C29572 NCIT_P98 "DR1 interacts with the TATA-binding protein (TBP) of TFIID and prevents formation of an active transcription complex by precluding TFIIA and/or TFIIB entry into the preinitiation complex. DRAP1 and DR1 interaction is required for corepressor function and stabilizes the TBP-DR1-DNA complex. DRAP1 protein contains a histone fold motif at the N terminus and a proline-rich region at the C terminus. The binding of DRAP1 to DR1 is dependent on the histone fold motif present in each protein. DRAP1 expression facilitates the maintenance of a differentiated state by silencing specific genes." @default.
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- NCIT_C29572 NCIT_R50 NCIT_C13426 @default.
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- NCIT_C29572 NCIT_R52 NCIT_C26199 @default.
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- NCIT_C29572 NCIT_R53 NCIT_C16521 @default.
- NCIT_C29572 NCIT_R53 NCIT_C17710 @default.
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- NCIT_C29572 NCIT_R53 NCIT_C18219 @default.
- NCIT_C29572 NCIT_R53 NCIT_C18469 @default.
- NCIT_C29572 NCIT_R53 NCIT_C19077 @default.
- NCIT_C29572 NCIT_R53 NCIT_C19986 @default.
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- NCIT_C29572 NCIT_R54 NCIT_C20194 @default.
- NCIT_C29572 NCIT_R54 NCIT_C20420 @default.
- NCIT_C29572 NCIT_R54 NCIT_C20599 @default.
- NCIT_C29572 NCIT_R54 NCIT_C20601 @default.
- NCIT_C29572 NCIT_R54 NCIT_C54362 @default.
- NCIT_C29572 normalizedInformationContent "100" @default.
- NCIT_C29572 referenceCount "1" @default.
- NCIT_C29572 hasExactSynonym "DR1-Associated Protein 1" @default.
- NCIT_C29572 hasExactSynonym "DRAP1" @default.
- NCIT_C29572 hasExactSynonym "Dr1-Associated Corepressor" @default.
- NCIT_C29572 hasExactSynonym "NC2-Alpha" @default.
- NCIT_C29572 hasExactSynonym "Negative Cofactor 2 Alpha" @default.
- NCIT_C29572 type Class @default.
- NCIT_C29572 isDefinedBy ncit.owl @default.
- NCIT_C29572 label "Dr1-Associated Corepressor" @default.
- NCIT_C29572 subClassOf B1c5a5b37427ca3d48913647f8fe3cea1 @default.
- NCIT_C29572 subClassOf B42ec50c6ea0518628450833a0e77fa83 @default.
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- NCIT_C29572 subClassOf NCIT_C17021 @default.
- NCIT_C29572 subClassOf NCIT_C18466 @default.
- NCIT_C29572 subClassOf NCIT_C20027 @default.
- NCIT_C29572 subClassOf NCIT_C26199 @default.
- NCIT_C29572 subClassOf NCIT_C26548 @default.
- NCIT_C29572 subClassOf NCIT_C29572 @default.