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- NCIT_C29619 IAO_0000115 "The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice." @default.
- NCIT_C29619 NCIT_NHC0 "C29619" @default.
- NCIT_C29619 NCIT_P106 "Hormone" @default.
- NCIT_C29619 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C29619 NCIT_P108 "Dihydrotestosterone" @default.
- NCIT_C29619 NCIT_P208 "CL512804" @default.
- NCIT_C29619 NCIT_P325 "A hormone made from testosterone in the prostate, testes, and certain other tissues. It is needed to develop and maintain male sex characteristics, such as facial hair, deep voice, and muscle growth. High amounts of androstanolone may increase the growth of prostate cancer and make it harder to treat." @default.
- NCIT_C29619 NCIT_P329 "511037" @default.
- NCIT_C29619 NCIT_P330 "511037" @default.
- NCIT_C29619 NCIT_P366 "Androstanolone" @default.
- NCIT_C29619 NCIT_P399 "511037" @default.
- NCIT_C29619 normalizedInformationContent "100" @default.
- NCIT_C29619 referenceCount "1" @default.
- NCIT_C29619 hasExactSynonym "(5alpha,17beta)-17-Hydroxyandrostan-3-one" @default.
- NCIT_C29619 hasExactSynonym "Androstanolone" @default.
- NCIT_C29619 hasExactSynonym "DHT" @default.
- NCIT_C29619 hasExactSynonym "Dihydrotestosterone" @default.
- NCIT_C29619 hasExactSynonym "androstanolone" @default.
- NCIT_C29619 hasExactSynonym "dihydrotestosterone" @default.
- NCIT_C29619 inSubset NCIT_C176424 @default.
- NCIT_C29619 type Class @default.
- NCIT_C29619 isDefinedBy ncit.owl @default.
- NCIT_C29619 label "Dihydrotestosterone" @default.
- NCIT_C29619 subClassOf NCIT_C1899 @default.
- NCIT_C29619 subClassOf NCIT_C1908 @default.
- NCIT_C29619 subClassOf NCIT_C1913 @default.
- NCIT_C29619 subClassOf NCIT_C2289 @default.
- NCIT_C29619 subClassOf NCIT_C2298 @default.
- NCIT_C29619 subClassOf NCIT_C2315 @default.
- NCIT_C29619 subClassOf NCIT_C29619 @default.
- NCIT_C29619 subClassOf NCIT_C616 @default.
- NCIT_C29619 subClassOf NCIT_C718 @default.
- NCIT_C29619 subClassOf NCIT_C843 @default.