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- NCIT_C29676 IAO_0000115 "Transcription initiation factor IIB (316 aa, ~95 kDa) is encoded by the human GTF2B gene. This protein plays a role in the initiation of RNA polymerase II-mediated gene transcription." @default.
- NCIT_C29676 NCIT_NHC0 "C29676" @default.
- NCIT_C29676 NCIT_P100 "189963" @default.
- NCIT_C29676 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C29676 NCIT_P106 "Biologically Active Substance" @default.
- NCIT_C29676 NCIT_P108 "Transcription Initiation Factor IIB" @default.
- NCIT_C29676 NCIT_P207 "C1333809" @default.
- NCIT_C29676 NCIT_P366 "General_Transcription_Factor-TFIIB" @default.
- NCIT_C29676 NCIT_P93 "Q00403" @default.
- NCIT_C29676 NCIT_P98 "General Transcription Factor TFIIB plays a central role in assembly of the preinitiation complex, required for transcription initiation by RNA polymerase II. Sequence-specific DNA-binding TFIIB forms the DAB complex with promoter-bound TFIID and TFIIA, bridging TFIID and RNA Polymerase II. TFIIB interacts with the promoter TFIIB-recognition element BRE. BRE suppresses basal transcription by a core promoter, which increases transcription in the presence of an activator that can disrupt promoter-bound TFIIB-BRE." @default.
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- NCIT_C29676 normalizedInformationContent "100" @default.
- NCIT_C29676 referenceCount "1" @default.
- NCIT_C29676 hasExactSynonym "GTF2B" @default.
- NCIT_C29676 hasExactSynonym "General Transcription Factor IIB" @default.
- NCIT_C29676 hasExactSynonym "General Transcription Factor TFIIB" @default.
- NCIT_C29676 hasExactSynonym "RNA Polymerase II Transcription Factor IIB" @default.
- NCIT_C29676 hasExactSynonym "S300-II" @default.
- NCIT_C29676 hasExactSynonym "Transcription Initiation Factor IIB" @default.
- NCIT_C29676 type Class @default.
- NCIT_C29676 isDefinedBy ncit.owl @default.
- NCIT_C29676 label "Transcription Initiation Factor IIB" @default.
- NCIT_C29676 subClassOf NCIT_C17021 @default.
- NCIT_C29676 subClassOf NCIT_C17207 @default.
- NCIT_C29676 subClassOf NCIT_C18466 @default.
- NCIT_C29676 subClassOf NCIT_C19851 @default.
- NCIT_C29676 subClassOf NCIT_C20027 @default.
- NCIT_C29676 subClassOf NCIT_C26199 @default.
- NCIT_C29676 subClassOf NCIT_C26548 @default.
- NCIT_C29676 subClassOf NCIT_C29676 @default.
- NCIT_C29676 equivalentClass Bbcc4f57632826d2f4bcec8b38387a05f @default.
- NCIT_C29676 equivalentClass Bff31ec0fcfabbb375dc17476b0ed8f42 @default.