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- NCIT_C30090 IAO_0000115 "The 4 major small nuclear ribonucleoprotein particles (snRNPs), U1, U2, U4/U6, and U5, are essential components of the eukaryotic pre-mRNA splicing machinery. These snRNPs share 8 proteins which form the snRNP structural core: SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, and SNRPG. These common proteins play an essential role in the biogenesis of the snRNPs. The assembly of the common proteins onto the small nuclear RNA (snRNA) appears to occur in at least 2 steps and involves the formation of RNA-free protein heterooligomers. The common proteins are referred to as Sm proteins because they represent the major targets for the anti-Sm autoantibodies which are diagnostic for SLE. (from OMIM and Swiss-Prot)" @default.
- NCIT_C30090 NCIT_NHC0 "C30090" @default.
- NCIT_C30090 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C30090 NCIT_P108 "snRNP Structural Core Protein" @default.
- NCIT_C30090 NCIT_P207 "C1337055" @default.
- NCIT_C30090 NCIT_P366 "snRNP_Structural_Core_Protein" @default.
- NCIT_C30090 NCIT_R51 NCIT_C21176 @default.
- NCIT_C30090 NCIT_R51 NCIT_C26548 @default.
- NCIT_C30090 NCIT_R51 NCIT_C28440 @default.
- NCIT_C30090 NCIT_R51 NCIT_C95949 @default.
- NCIT_C30090 NCIT_R54 NCIT_C16612 @default.
- NCIT_C30090 NCIT_R54 NCIT_C20744 @default.
- NCIT_C30090 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C30090 referenceCount "3" @default.
- NCIT_C30090 hasExactSynonym "Sm Protein" @default.
- NCIT_C30090 hasExactSynonym "Small Nuclear Ribonucleoprotein Particle Structural Core Protein" @default.
- NCIT_C30090 hasExactSynonym "snRNP Structural Core Protein" @default.
- NCIT_C30090 type Class @default.
- NCIT_C30090 isDefinedBy ncit.owl @default.
- NCIT_C30090 label "snRNP Structural Core Protein" @default.
- NCIT_C30090 subClassOf B09fe2350135ff7d1a4c52961b460ca74 @default.
- NCIT_C30090 subClassOf B3a268d61dc2e65670d3647ca55d4f62d @default.
- NCIT_C30090 subClassOf NCIT_C17021 @default.
- NCIT_C30090 subClassOf NCIT_C18073 @default.
- NCIT_C30090 subClassOf NCIT_C20027 @default.
- NCIT_C30090 subClassOf NCIT_C26548 @default.
- NCIT_C30090 subClassOf NCIT_C30090 @default.