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- NCIT_C321 IAO_0000115 "A synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription. (NCI04)" @default.
- NCIT_C321 NCIT_A24 NCIT_C274 @default.
- NCIT_C321 NCIT_A32 NCIT_C1909 @default.
- NCIT_C321 NCIT_NHC0 "C321" @default.
- NCIT_C321 NCIT_P106 "Organic Chemical" @default.
- NCIT_C321 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C321 NCIT_P107 "Busulfan" @default.
- NCIT_C321 NCIT_P108 "Busulfan" @default.
- NCIT_C321 NCIT_P175 "750" @default.
- NCIT_C321 NCIT_P207 "C0006463" @default.
- NCIT_C321 NCIT_P210 "55-98-1" @default.
- NCIT_C321 NCIT_P302 "Bone marrow disorders; chronic myelogenous leukemia; palliative; neoadjuvant to allogeneic hematopoietic progenitor cell transplantation; neoplastic meningitis; primary brain malignancies" @default.
- NCIT_C321 NCIT_P319 "G1LN9045DK" @default.
- NCIT_C321 NCIT_P322 "CTRP" @default.
- NCIT_C321 NCIT_P322 "FDA" @default.
- NCIT_C321 NCIT_P322 "GDC" @default.
- NCIT_C321 NCIT_P322 "PCDC" @default.
- NCIT_C321 NCIT_P325 "An anticancer drug that belongs to the family of drugs called alkylating agents." @default.
- NCIT_C321 NCIT_P329 "41947" @default.
- NCIT_C321 NCIT_P330 "41947" @default.
- NCIT_C321 NCIT_P350 "C6H14O6S2" @default.
- NCIT_C321 NCIT_P366 "Busulfan" @default.
- NCIT_C321 NCIT_P368 "CHEBI:28901" @default.
- NCIT_C321 NCIT_P375 "Busulfan" @default.
- NCIT_C321 NCIT_P399 "41947" @default.
- NCIT_C321 normalizedInformationContent "77.066663625307044" @default.
- NCIT_C321 referenceCount "32" @default.
- NCIT_C321 hasExactSynonym "1, 4-Bis[methanesulfonoxy]butane" @default.
- NCIT_C321 hasExactSynonym "1,4-Bis(methanesulfonoxy)butane" @default.
- NCIT_C321 hasExactSynonym "1,4-Bitanediol Dimethanesulfonate Esters" @default.
- NCIT_C321 hasExactSynonym "1,4-Butanediol Dimethylsulfonate" @default.
- NCIT_C321 hasExactSynonym "1,4-Di(methanesulfonyloxy)butane" @default.
- NCIT_C321 hasExactSynonym "1,4-Di(methylsulfonyloxy)butane" @default.
- NCIT_C321 hasExactSynonym "BUS" @default.
- NCIT_C321 hasExactSynonym "BUSULFAN" @default.
- NCIT_C321 hasExactSynonym "Busilvex" @default.
- NCIT_C321 hasExactSynonym "Bussulfam" @default.
- NCIT_C321 hasExactSynonym "Busulfan" @default.
- NCIT_C321 hasExactSynonym "Busulfanum" @default.
- NCIT_C321 hasExactSynonym "Busulfex" @default.
- NCIT_C321 hasExactSynonym "Busulphan" @default.
- NCIT_C321 hasExactSynonym "CB 2041" @default.
- NCIT_C321 hasExactSynonym "CB-2041" @default.
- NCIT_C321 hasExactSynonym "GT 41" @default.
- NCIT_C321 hasExactSynonym "GT-41" @default.
- NCIT_C321 hasExactSynonym "Glyzophrol" @default.
- NCIT_C321 hasExactSynonym "Joacamine" @default.
- NCIT_C321 hasExactSynonym "Methanesulfonic Acid Tetramethylene Ester" @default.
- NCIT_C321 hasExactSynonym "Methanesulfonic acid, tetramethylene ester" @default.
- NCIT_C321 hasExactSynonym "Mielucin" @default.
- NCIT_C321 hasExactSynonym "Misulban" @default.
- NCIT_C321 hasExactSynonym "Misulfan" @default.
- NCIT_C321 hasExactSynonym "Mitosan" @default.
- NCIT_C321 hasExactSynonym "Myeleukon" @default.
- NCIT_C321 hasExactSynonym "Myeloleukon" @default.
- NCIT_C321 hasExactSynonym "Myelosan" @default.
- NCIT_C321 hasExactSynonym "Mylecytan" @default.
- NCIT_C321 hasExactSynonym "Myleran" @default.
- NCIT_C321 hasExactSynonym "Sulfabutin" @default.
- NCIT_C321 hasExactSynonym "Tetramethylene Bis(methanesulfonate)" @default.
- NCIT_C321 hasExactSynonym "Tetramethylene bis[methanesulfonate]" @default.
- NCIT_C321 hasExactSynonym "WR-19508" @default.
- NCIT_C321 hasExactSynonym "busulfan" @default.
- NCIT_C321 inSubset NCIT_C116977 @default.
- NCIT_C321 inSubset NCIT_C116978 @default.
- NCIT_C321 inSubset NCIT_C128784 @default.
- NCIT_C321 inSubset NCIT_C157711 @default.
- NCIT_C321 inSubset NCIT_C157712 @default.
- NCIT_C321 inSubset NCIT_C173234 @default.
- NCIT_C321 inSubset NCIT_C174019 @default.
- NCIT_C321 inSubset NCIT_C176424 @default.
- NCIT_C321 inSubset NCIT_C177537 @default.
- NCIT_C321 inSubset NCIT_C186327 @default.
- NCIT_C321 inSubset NCIT_C186328 @default.
- NCIT_C321 inSubset NCIT_C186341 @default.
- NCIT_C321 inSubset NCIT_C63923 @default.
- NCIT_C321 type Class @default.
- NCIT_C321 isDefinedBy ncit.owl @default.
- NCIT_C321 label "Busulfan" @default.
- NCIT_C321 subClassOf NCIT_C1590 @default.
- NCIT_C321 subClassOf NCIT_C186664 @default.
- NCIT_C321 subClassOf NCIT_C1908 @default.
- NCIT_C321 subClassOf NCIT_C1909 @default.
- NCIT_C321 subClassOf NCIT_C222 @default.
- NCIT_C321 subClassOf NCIT_C274 @default.
- NCIT_C321 subClassOf NCIT_C2842 @default.
- NCIT_C321 subClassOf NCIT_C321 @default.