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- NCIT_C338 IAO_0000115 "An alkaloid isolated from the Chinese tree Camptotheca acuminata, with antineoplastic activity. During the S phase of the cell cycle, camptothecin selectively stabilizes topoisomerase I-DNA covalent complexes, thereby inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when encountered by the DNA replication machinery. (NCI)" @default.
- NCIT_C338 NCIT_A32 NCIT_C1909 @default.
- NCIT_C338 NCIT_A5 NCIT_C2344 @default.
- NCIT_C338 NCIT_NHC0 "C338" @default.
- NCIT_C338 NCIT_P106 "Organic Chemical" @default.
- NCIT_C338 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C338 NCIT_P108 "Camptothecin" @default.
- NCIT_C338 NCIT_P175 "94600" @default.
- NCIT_C338 NCIT_P207 "C0006812" @default.
- NCIT_C338 NCIT_P210 "7689-03-4" @default.
- NCIT_C338 NCIT_P319 "XT3Z54Z28A" @default.
- NCIT_C338 NCIT_P322 "FDA" @default.
- NCIT_C338 NCIT_P322 "GDC" @default.
- NCIT_C338 NCIT_P325 "An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors." @default.
- NCIT_C338 NCIT_P329 "39173" @default.
- NCIT_C338 NCIT_P330 "39173" @default.
- NCIT_C338 NCIT_P350 "C20H16N2O4" @default.
- NCIT_C338 NCIT_P366 "Camptothecin" @default.
- NCIT_C338 NCIT_P368 "CHEBI:27656" @default.
- NCIT_C338 NCIT_P375 "Camptothecin" @default.
- NCIT_C338 NCIT_P399 "39173" @default.
- NCIT_C338 normalizedInformationContent "100" @default.
- NCIT_C338 referenceCount "1" @default.
- NCIT_C338 hasExactSynonym "(+)-Camptothecin" @default.
- NCIT_C338 hasExactSynonym "(S)-4-ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolozino[1,2-b]quinoline-3,14(4H,12H)-dione" @default.
- NCIT_C338 hasExactSynonym "1H-Pyrano[3',3'.6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4hydroxy-(S)-(9CI)" @default.
- NCIT_C338 hasExactSynonym "20(S)-Camptothecine" @default.
- NCIT_C338 hasExactSynonym "20-(S)-camptothecine" @default.
- NCIT_C338 hasExactSynonym "21, 22-Secocamptothecin-21-oic acid lactone" @default.
- NCIT_C338 hasExactSynonym "21, 22-secocamptothecin-21-oic acid lactone" @default.
- NCIT_C338 hasExactSynonym "CAMPTOTHECIN" @default.
- NCIT_C338 hasExactSynonym "Camptothecin" @default.
- NCIT_C338 hasExactSynonym "camptothecin" @default.
- NCIT_C338 hasExactSynonym "camptothecine" @default.
- NCIT_C338 inSubset NCIT_C128784 @default.
- NCIT_C338 inSubset NCIT_C157711 @default.
- NCIT_C338 inSubset NCIT_C157712 @default.
- NCIT_C338 inSubset NCIT_C176424 @default.
- NCIT_C338 inSubset NCIT_C177537 @default.
- NCIT_C338 inSubset NCIT_C63923 @default.
- NCIT_C338 type Class @default.
- NCIT_C338 isDefinedBy ncit.owl @default.
- NCIT_C338 label "Camptothecin" @default.
- NCIT_C338 subClassOf NCIT_C129824 @default.
- NCIT_C338 subClassOf NCIT_C129825 @default.
- NCIT_C338 subClassOf NCIT_C1748 @default.
- NCIT_C338 subClassOf NCIT_C1904 @default.
- NCIT_C338 subClassOf NCIT_C1908 @default.
- NCIT_C338 subClassOf NCIT_C1909 @default.
- NCIT_C338 subClassOf NCIT_C2189 @default.
- NCIT_C338 subClassOf NCIT_C274 @default.
- NCIT_C338 subClassOf NCIT_C338 @default.
- NCIT_C338 subClassOf NCIT_C471 @default.