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- NCIT_C343 IAO_0000115 "A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis." @default.
- NCIT_C343 NCIT_A5 NCIT_C65285 @default.
- NCIT_C343 NCIT_NHC0 "C343" @default.
- NCIT_C343 NCIT_P106 "Antibiotic" @default.
- NCIT_C343 NCIT_P106 "Organic Chemical" @default.
- NCIT_C343 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C343 NCIT_P108 "Carbenicillin" @default.
- NCIT_C343 NCIT_P207 "C0006976" @default.
- NCIT_C343 NCIT_P210 "4697-36-3" @default.
- NCIT_C343 NCIT_P319 "G42ZU72N5G" @default.
- NCIT_C343 NCIT_P322 "FDA" @default.
- NCIT_C343 NCIT_P329 "39174" @default.
- NCIT_C343 NCIT_P330 "39174" @default.
- NCIT_C343 NCIT_P350 "C17H18N2O6S" @default.
- NCIT_C343 NCIT_P366 "Carbenicillin" @default.
- NCIT_C343 NCIT_P368 "CHEBI:3393" @default.
- NCIT_C343 NCIT_P399 "39174" @default.
- NCIT_C343 normalizedInformationContent "100" @default.
- NCIT_C343 referenceCount "1" @default.
- NCIT_C343 hasExactSynonym "CARBENICILLIN" @default.
- NCIT_C343 hasExactSynonym "Carbenicillin" @default.
- NCIT_C343 hasExactSynonym "Geopen" @default.
- NCIT_C343 hasExactSynonym "Pyopen" @default.
- NCIT_C343 inSubset NCIT_C176424 @default.
- NCIT_C343 inSubset NCIT_C63923 @default.
- NCIT_C343 type Class @default.
- NCIT_C343 isDefinedBy ncit.owl @default.
- NCIT_C343 label "Carbenicillin" @default.
- NCIT_C343 subClassOf NCIT_C1500 @default.
- NCIT_C343 subClassOf NCIT_C1558 @default.
- NCIT_C343 subClassOf NCIT_C1908 @default.
- NCIT_C343 subClassOf NCIT_C1909 @default.
- NCIT_C343 subClassOf NCIT_C254 @default.
- NCIT_C343 subClassOf NCIT_C258 @default.
- NCIT_C343 subClassOf NCIT_C260 @default.
- NCIT_C343 subClassOf NCIT_C343 @default.