Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C346> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- NCIT_C346 IAO_0000115 "A zinc-dependent enzyme isolated from a strain of the bacterium Pseudomonas. Because glucarpidase rapidly hydrolyzes methotrexate into inactive metabolites, it may be useful as a rescue agent for methotrexate-induced nephrotoxicity. In antibody-directed enzyme prodrug therapy (ADEPT), this agent is conjugated with an antibody that binds to a specific tumor cell type, allowing for glucarpidase-catalyzed activation of a co-administered prodrug at the site of the tumor." @default.
- NCIT_C346 NCIT_A32 NCIT_C1909 @default.
- NCIT_C346 NCIT_A7 NCIT_C642 @default.
- NCIT_C346 NCIT_NHC0 "C346" @default.
- NCIT_C346 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C346 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C346 NCIT_P107 "Glucarpidase" @default.
- NCIT_C346 NCIT_P108 "Glucarpidase" @default.
- NCIT_C346 NCIT_P175 "641273" @default.
- NCIT_C346 NCIT_P175 "732443" @default.
- NCIT_C346 NCIT_P207 "C0007072" @default.
- NCIT_C346 NCIT_P210 "9074-87-7" @default.
- NCIT_C346 NCIT_P319 "2GFP9BJD79" @default.
- NCIT_C346 NCIT_P322 "CTRP" @default.
- NCIT_C346 NCIT_P322 "FDA" @default.
- NCIT_C346 NCIT_P322 "GDC" @default.
- NCIT_C346 NCIT_P325 "A bacterial enzyme that breaks down proteins and other substances, including methotrexate. It is being studied in the treatment of toxic effects caused by methotrexate. It may also help activate certain drugs to kill cancer cells. It is a type of chemoprotective agent and a type of prodrug activator." @default.
- NCIT_C346 NCIT_P329 "41665" @default.
- NCIT_C346 NCIT_P330 "41665" @default.
- NCIT_C346 NCIT_P350 "C20H20O4" @default.
- NCIT_C346 NCIT_P366 "Carboxypeptidase-G2" @default.
- NCIT_C346 NCIT_P375 "Glucarpidase" @default.
- NCIT_C346 NCIT_P399 "41665" @default.
- NCIT_C346 NCIT_R124 NCIT_C17710 @default.
- NCIT_C346 NCIT_R124 NCIT_C17828 @default.
- NCIT_C346 NCIT_R124 NCIT_C18219 @default.
- NCIT_C346 NCIT_R124 NCIT_C19986 @default.
- NCIT_C346 NCIT_R124 NCIT_C41556 @default.
- NCIT_C346 NCIT_R125 NCIT_C16841 @default.
- NCIT_C346 NCIT_R125 NCIT_C17710 @default.
- NCIT_C346 NCIT_R125 NCIT_C17828 @default.
- NCIT_C346 NCIT_R125 NCIT_C19536 @default.
- NCIT_C346 NCIT_R125 NCIT_C19988 @default.
- NCIT_C346 NCIT_R125 NCIT_C28498 @default.
- NCIT_C346 NCIT_R125 NCIT_C41479 @default.
- NCIT_C346 NCIT_R125 NCIT_C41578 @default.
- NCIT_C346 NCIT_R125 NCIT_C41590 @default.
- NCIT_C346 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C346 referenceCount "2" @default.
- NCIT_C346 hasExactSynonym "Acetylaspartylglutamate Dipeptidase" @default.
- NCIT_C346 hasExactSynonym "CPDG2" @default.
- NCIT_C346 hasExactSynonym "CPG2" @default.
- NCIT_C346 hasExactSynonym "Carboxypeptidase G2" @default.
- NCIT_C346 hasExactSynonym "GLUCARPIDASE" @default.
- NCIT_C346 hasExactSynonym "Glucarpidase" @default.
- NCIT_C346 hasExactSynonym "Poly(gamma-glutamic Acid) Endohydrolase" @default.
- NCIT_C346 hasExactSynonym "Pteroylpolygammaglutamyl Hydrolase" @default.
- NCIT_C346 hasExactSynonym "Voraxaze" @default.
- NCIT_C346 hasExactSynonym "carboxypeptidase-G2" @default.
- NCIT_C346 inSubset NCIT_C116977 @default.
- NCIT_C346 inSubset NCIT_C116978 @default.
- NCIT_C346 inSubset NCIT_C128784 @default.
- NCIT_C346 inSubset NCIT_C157711 @default.
- NCIT_C346 inSubset NCIT_C157712 @default.
- NCIT_C346 inSubset NCIT_C176424 @default.
- NCIT_C346 inSubset NCIT_C177537 @default.
- NCIT_C346 inSubset NCIT_C63923 @default.
- NCIT_C346 type Class @default.
- NCIT_C346 isDefinedBy ncit.owl @default.
- NCIT_C346 label "Glucarpidase" @default.
- NCIT_C346 subClassOf NCIT_C1908 @default.
- NCIT_C346 subClassOf NCIT_C1909 @default.
- NCIT_C346 subClassOf NCIT_C29726 @default.
- NCIT_C346 subClassOf NCIT_C307 @default.
- NCIT_C346 subClassOf NCIT_C346 @default.
- NCIT_C346 equivalentClass B05a72098ddc81c1b28ad1d433c99aa5d @default.
- NCIT_C346 equivalentClass B1543dbbcda33a33f8fbf10b23cd1db27 @default.