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- NCIT_C354 IAO_0000115 "A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis." @default.
- NCIT_C354 NCIT_A5 NCIT_C2328 @default.
- NCIT_C354 NCIT_NHC0 "C354" @default.
- NCIT_C354 NCIT_P106 "Antibiotic" @default.
- NCIT_C354 NCIT_P106 "Organic Chemical" @default.
- NCIT_C354 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C354 NCIT_P108 "Cefotaxime" @default.
- NCIT_C354 NCIT_P207 "C0007554" @default.
- NCIT_C354 NCIT_P210 "63527-52-6" @default.
- NCIT_C354 NCIT_P319 "N2GI8B1GK7" @default.
- NCIT_C354 NCIT_P322 "FDA" @default.
- NCIT_C354 NCIT_P329 "39177" @default.
- NCIT_C354 NCIT_P330 "39177" @default.
- NCIT_C354 NCIT_P350 "C16H17N5O7S2" @default.
- NCIT_C354 NCIT_P366 "Cefotaxime" @default.
- NCIT_C354 NCIT_P368 "CHEBI:204928" @default.
- NCIT_C354 NCIT_P399 "39177" @default.
- NCIT_C354 normalizedInformationContent "100" @default.
- NCIT_C354 referenceCount "1" @default.
- NCIT_C354 hasExactSynonym "CEFOTAXIME" @default.
- NCIT_C354 hasExactSynonym "Cefotaxime" @default.
- NCIT_C354 inSubset NCIT_C176424 @default.
- NCIT_C354 inSubset NCIT_C63923 @default.
- NCIT_C354 type Class @default.
- NCIT_C354 isDefinedBy ncit.owl @default.
- NCIT_C354 label "Cefotaxime" @default.
- NCIT_C354 subClassOf NCIT_C1908 @default.
- NCIT_C354 subClassOf NCIT_C1909 @default.
- NCIT_C354 subClassOf NCIT_C254 @default.
- NCIT_C354 subClassOf NCIT_C258 @default.
- NCIT_C354 subClassOf NCIT_C260 @default.
- NCIT_C354 subClassOf NCIT_C354 @default.
- NCIT_C354 subClassOf NCIT_C357 @default.