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- NCIT_C356 IAO_0000115 "A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to second and third generation cephalosporins, cephalexin is more active against gram-positive and less active against gram-negative organisms." @default.
- NCIT_C356 NCIT_A5 NCIT_C47969 @default.
- NCIT_C356 NCIT_NHC0 "C356" @default.
- NCIT_C356 NCIT_P106 "Antibiotic" @default.
- NCIT_C356 NCIT_P106 "Organic Chemical" @default.
- NCIT_C356 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C356 NCIT_P107 "Cephalexin" @default.
- NCIT_C356 NCIT_P108 "Cephalexin" @default.
- NCIT_C356 NCIT_P207 "C0007716" @default.
- NCIT_C356 NCIT_P210 "23325-78-2" @default.
- NCIT_C356 NCIT_P319 "OBN7UDS42Y" @default.
- NCIT_C356 NCIT_P322 "CTRP" @default.
- NCIT_C356 NCIT_P322 "FDA" @default.
- NCIT_C356 NCIT_P325 "An antibiotic drug that belongs to the family of drugs called cephalosporins." @default.
- NCIT_C356 NCIT_P329 "43417" @default.
- NCIT_C356 NCIT_P330 "43417" @default.
- NCIT_C356 NCIT_P350 "C16H17N3O4S.H2O" @default.
- NCIT_C356 NCIT_P366 "Cephalexin" @default.
- NCIT_C356 NCIT_P368 "CHEBI:3535" @default.
- NCIT_C356 NCIT_P399 "43417" @default.
- NCIT_C356 normalizedInformationContent "100" @default.
- NCIT_C356 referenceCount "1" @default.
- NCIT_C356 hasExactSynonym "CEPHALEXIN" @default.
- NCIT_C356 hasExactSynonym "Cephalexin" @default.
- NCIT_C356 hasExactSynonym "Keflex" @default.
- NCIT_C356 hasExactSynonym "cephalexin" @default.
- NCIT_C356 inSubset NCIT_C116977 @default.
- NCIT_C356 inSubset NCIT_C116978 @default.
- NCIT_C356 inSubset NCIT_C176424 @default.
- NCIT_C356 inSubset NCIT_C63923 @default.
- NCIT_C356 type Class @default.
- NCIT_C356 isDefinedBy ncit.owl @default.
- NCIT_C356 label "Cephalexin" @default.
- NCIT_C356 subClassOf NCIT_C1908 @default.
- NCIT_C356 subClassOf NCIT_C1909 @default.
- NCIT_C356 subClassOf NCIT_C254 @default.
- NCIT_C356 subClassOf NCIT_C258 @default.
- NCIT_C356 subClassOf NCIT_C260 @default.
- NCIT_C356 subClassOf NCIT_C356 @default.
- NCIT_C356 subClassOf NCIT_C357 @default.