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- NCIT_C357 IAO_0000115 "A synthetic or semi-synthetic beta-lactam antibiotic derived from Acremonium (Cephalosporium) fungi with bactericidal activity. Cephalosporin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.
- NCIT_C357 NCIT_NHC0 "C357" @default.
- NCIT_C357 NCIT_P106 "Chemical Viewed Functionally" @default.
- NCIT_C357 NCIT_P108 "Cephalosporin Antibiotic" @default.
- NCIT_C357 NCIT_P208 "CL557638" @default.
- NCIT_C357 NCIT_P325 "A drug used to treat bacterial infections. It belongs to the family of drugs called antibiotics." @default.
- NCIT_C357 NCIT_P366 "Cephalosporin_Antibiotic" @default.
- NCIT_C357 NCIT_P368 "CHEBI:23066" @default.
- NCIT_C357 normalizedInformationContent "66.375523459856723" @default.
- NCIT_C357 referenceCount "161" @default.
- NCIT_C357 hasExactSynonym "Cephalosporin Antibiotic" @default.
- NCIT_C357 hasExactSynonym "Cephalosporins" @default.
- NCIT_C357 hasExactSynonym "cephalosporin" @default.
- NCIT_C357 type Class @default.
- NCIT_C357 isDefinedBy ncit.owl @default.
- NCIT_C357 label "Cephalosporin Antibiotic" @default.
- NCIT_C357 subClassOf NCIT_C1908 @default.
- NCIT_C357 subClassOf NCIT_C1909 @default.
- NCIT_C357 subClassOf NCIT_C254 @default.
- NCIT_C357 subClassOf NCIT_C258 @default.
- NCIT_C357 subClassOf NCIT_C260 @default.
- NCIT_C357 subClassOf NCIT_C357 @default.