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- NCIT_C37274 IAO_0000115 "Human Interferon Alpha Receptor Complex (Type II Cytokine Family Receptor) is a ubiquitous type I membrane protein heteromeric receptor for type I IFNs, alpha and beta, composed of at least 2 chains, IFNAR1 (alpha chain) and IFNAR2 (beta chain). In mediating innate immune responses to viral infection and specific interferon inhibition of virus replication, binding of alpha and beta IFNs triggers tyrosine phosphorylation of JAKs, TYK2, STAT proteins, autophosphorylation, and tyrosine phosphorylation by TYK2. (NCI)" @default.
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- NCIT_C37274 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C37274 NCIT_P106 "Receptor" @default.
- NCIT_C37274 NCIT_P107 "Interferon Alpha Receptor Complex" @default.
- NCIT_C37274 NCIT_P108 "Interferon Alpha Receptor Complex" @default.
- NCIT_C37274 NCIT_P207 "C0254653" @default.
- NCIT_C37274 NCIT_P322 "CTRP" @default.
- NCIT_C37274 NCIT_P366 "Interferon_Alpha_Receptor_Complex" @default.
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- NCIT_C37274 hasExactSynonym "Interferon Alpha Receptor Complex" @default.
- NCIT_C37274 hasExactSynonym "Interferon Alpha Receptor" @default.
- NCIT_C37274 hasExactSynonym "Interferon Beta Receptor" @default.
- NCIT_C37274 hasExactSynonym "Interferon-Alpha-Beta Receptor" @default.
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