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- NCIT_C37294 IAO_0000115 "Voltage-dependent anion-selective channel protein 2 (294 aa, ~32 kDa) is encoded by the human VDAC2 gene. This protein is involved in mitochondrial outer membrane permeability." @default.
- NCIT_C37294 NCIT_NHC0 "C37294" @default.
- NCIT_C37294 NCIT_P100 "193245" @default.
- NCIT_C37294 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C37294 NCIT_P107 "Voltage-Dependent Anion-Selective Channel Protein 2" @default.
- NCIT_C37294 NCIT_P108 "Voltage-Dependent Anion-Selective Channel Protein 2" @default.
- NCIT_C37294 NCIT_P207 "C1530761" @default.
- NCIT_C37294 NCIT_P322 "CTRP" @default.
- NCIT_C37294 NCIT_P366 "Voltage-Dependent_Anion_Channel-2" @default.
- NCIT_C37294 NCIT_P93 "P45880" @default.
- NCIT_C37294 NCIT_P98 "Voltage-dependent anion-selective channel protein 2 (VDAC2) interacts specifically with inactive BAK, preventing BAK activation and inhibiting the mitochondrial apoptotic pathway. Apoptotic signals activate BH3-molecules such as tBID, BIM, or BAD, which displace VDAC2 from BAK, enabling BAK homooligomerization and apoptosis. VDAC2 is also the mitochondrial binding site of metabolic enzymes hexokinase and glycerol kinase." @default.
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- NCIT_C37294 normalizedInformationContent "100" @default.
- NCIT_C37294 referenceCount "1" @default.
- NCIT_C37294 hasExactSynonym "Outer Mitochondrial Membrane Protein Porin 2" @default.
- NCIT_C37294 hasExactSynonym "Outer Mitochondrial Membrane Protein Porin-2" @default.
- NCIT_C37294 hasExactSynonym "VDAC-2" @default.
- NCIT_C37294 hasExactSynonym "Voltage-Dependent Anion Channel-2" @default.
- NCIT_C37294 hasExactSynonym "Voltage-Dependent Anion-Selective Channel Protein 2" @default.
- NCIT_C37294 hasExactSynonym "Voltage-Dependent Anion-Selective Channel Protein-2" @default.
- NCIT_C37294 hasExactSynonym "hVDAC2" @default.
- NCIT_C37294 inSubset NCIT_C116977 @default.
- NCIT_C37294 inSubset NCIT_C142799 @default.
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- NCIT_C37294 type Class @default.
- NCIT_C37294 isDefinedBy ncit.owl @default.
- NCIT_C37294 label "Voltage-Dependent Anion-Selective Channel Protein 2" @default.
- NCIT_C37294 subClassOf NCIT_C16386 @default.
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