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- NCIT_C38126 IAO_0000115 "A pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Although originally thought to exhibit specific cytotoxicity against melanoma cells, this agent has been found to be cytotoxic against non-melanoma tumor cell types including neuroectodermal and brain tumor cells." @default.
- NCIT_C38126 NCIT_A32 NCIT_C1909 @default.
- NCIT_C38126 NCIT_NHC0 "C38126" @default.
- NCIT_C38126 NCIT_P106 "Organic Chemical" @default.
- NCIT_C38126 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C38126 NCIT_P107 "Betulinic Acid" @default.
- NCIT_C38126 NCIT_P108 "Betulinic Acid" @default.
- NCIT_C38126 NCIT_P175 "113090" @default.
- NCIT_C38126 NCIT_P207 "C0053530" @default.
- NCIT_C38126 NCIT_P210 "472-15-1" @default.
- NCIT_C38126 NCIT_P319 "4G6A18707N" @default.
- NCIT_C38126 NCIT_P322 "CTRP" @default.
- NCIT_C38126 NCIT_P322 "FDA" @default.
- NCIT_C38126 NCIT_P322 "GDC" @default.
- NCIT_C38126 NCIT_P329 "496932" @default.
- NCIT_C38126 NCIT_P330 "496932" @default.
- NCIT_C38126 NCIT_P350 "C30H48O3" @default.
- NCIT_C38126 NCIT_P366 "Betulinic_Acid" @default.
- NCIT_C38126 NCIT_P375 "Betulinic Acid" @default.
- NCIT_C38126 NCIT_P399 "496932" @default.
- NCIT_C38126 NCIT_R124 NCIT_C17710 @default.
- NCIT_C38126 NCIT_R124 NCIT_C17828 @default.
- NCIT_C38126 NCIT_R124 NCIT_C19986 @default.
- NCIT_C38126 NCIT_R124 NCIT_C40551 @default.
- NCIT_C38126 NCIT_R125 NCIT_C16397 @default.
- NCIT_C38126 NCIT_R125 NCIT_C16399 @default.
- NCIT_C38126 NCIT_R125 NCIT_C17828 @default.
- NCIT_C38126 NCIT_R125 NCIT_C18824 @default.
- NCIT_C38126 NCIT_R125 NCIT_C20150 @default.
- NCIT_C38126 NCIT_R125 NCIT_C20480 @default.
- NCIT_C38126 NCIT_R125 NCIT_C21102 @default.
- NCIT_C38126 NCIT_R125 NCIT_C40715 @default.
- NCIT_C38126 NCIT_R125 NCIT_C40738 @default.
- NCIT_C38126 NCIT_R125 NCIT_C41515 @default.
- NCIT_C38126 NCIT_R125 NCIT_C51037 @default.
- NCIT_C38126 normalizedInformationContent "100" @default.
- NCIT_C38126 referenceCount "1" @default.
- NCIT_C38126 hasExactSynonym "(3beta)-3-Hydroxy-lup-20(29)-en-28-oic Acid" @default.
- NCIT_C38126 hasExactSynonym "ALS-357" @default.
- NCIT_C38126 hasExactSynonym "BETULINIC ACID" @default.
- NCIT_C38126 hasExactSynonym "Betulinic Acid" @default.
- NCIT_C38126 hasExactSynonym "Mairin" @default.
- NCIT_C38126 inSubset NCIT_C116977 @default.
- NCIT_C38126 inSubset NCIT_C116978 @default.
- NCIT_C38126 inSubset NCIT_C128784 @default.
- NCIT_C38126 inSubset NCIT_C157711 @default.
- NCIT_C38126 inSubset NCIT_C157712 @default.
- NCIT_C38126 inSubset NCIT_C176424 @default.
- NCIT_C38126 inSubset NCIT_C177537 @default.
- NCIT_C38126 inSubset NCIT_C63923 @default.
- NCIT_C38126 type Class @default.
- NCIT_C38126 isDefinedBy ncit.owl @default.
- NCIT_C38126 label "Betulinic Acid" @default.
- NCIT_C38126 subClassOf B3f995f0442340bf6a0a72c039acf6ad4 @default.
- NCIT_C38126 subClassOf B5c239bc37f179c66b1b0f5d21497bab5 @default.
- NCIT_C38126 subClassOf B64657324d6ba742d2d34d594beaaa9ae @default.
- NCIT_C38126 subClassOf B80701d5c90e881fcf87acc3e9e69f4d1 @default.
- NCIT_C38126 subClassOf Bc348e34283bbdd973e37a9f8bb447ea5 @default.
- NCIT_C38126 subClassOf Bd986535d6ab72ee8854acb1db52cabf4 @default.
- NCIT_C38126 subClassOf Be9fbdd9782da047bd854b4e3abc13a83 @default.
- NCIT_C38126 subClassOf Bf8f4e61a8d2cce3deb438a527e268376 @default.
- NCIT_C38126 subClassOf NCIT_C1908 @default.
- NCIT_C38126 subClassOf NCIT_C1909 @default.
- NCIT_C38126 subClassOf NCIT_C2139 @default.
- NCIT_C38126 subClassOf NCIT_C308 @default.
- NCIT_C38126 subClassOf NCIT_C38126 @default.