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- NCIT_C38703 IAO_0000115 "A synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake. (NCI04)" @default.
- NCIT_C38703 NCIT_NHC0 "C38703" @default.
- NCIT_C38703 NCIT_P106 "Organic Chemical" @default.
- NCIT_C38703 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C38703 NCIT_P108 "Lamotrigine" @default.
- NCIT_C38703 NCIT_P207 "C0064636" @default.
- NCIT_C38703 NCIT_P210 "84057-84-1" @default.
- NCIT_C38703 NCIT_P302 "Epilepsy" @default.
- NCIT_C38703 NCIT_P319 "U3H27498KS" @default.
- NCIT_C38703 NCIT_P322 "FDA" @default.
- NCIT_C38703 NCIT_P325 "A drug that is used to help control some types of seizures. It is being studied in the prevention of peripheral neuropathy caused by some chemotherapy drugs. It belongs to the family of drugs called anticonvulsants." @default.
- NCIT_C38703 NCIT_P329 "328241" @default.
- NCIT_C38703 NCIT_P330 "328241" @default.
- NCIT_C38703 NCIT_P350 "C9H7Cl2N5" @default.
- NCIT_C38703 NCIT_P366 "Lamotrigine" @default.
- NCIT_C38703 NCIT_P368 "CHEBI:6367" @default.
- NCIT_C38703 NCIT_P399 "328241" @default.
- NCIT_C38703 NCIT_P98 "Clinical Trial--Chemotherapy-induced neuropathy" @default.
- NCIT_C38703 normalizedInformationContent "100" @default.
- NCIT_C38703 referenceCount "1" @default.
- NCIT_C38703 hasExactSynonym "LAMOTRIGINE" @default.
- NCIT_C38703 hasExactSynonym "Lamictal" @default.
- NCIT_C38703 hasExactSynonym "Lamotrigine" @default.
- NCIT_C38703 hasExactSynonym "lamotrigine" @default.
- NCIT_C38703 inSubset NCIT_C176424 @default.
- NCIT_C38703 inSubset NCIT_C63923 @default.
- NCIT_C38703 type Class @default.
- NCIT_C38703 isDefinedBy ncit.owl @default.
- NCIT_C38703 label "Lamotrigine" @default.
- NCIT_C38703 subClassOf NCIT_C1908 @default.
- NCIT_C38703 subClassOf NCIT_C1909 @default.
- NCIT_C38703 subClassOf NCIT_C264 @default.
- NCIT_C38703 subClassOf NCIT_C38703 @default.
- NCIT_C38703 subClassOf NCIT_C78272 @default.