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- NCIT_C38709 IAO_0000115 "A synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)" @default.
- NCIT_C38709 NCIT_A32 NCIT_C1909 @default.
- NCIT_C38709 NCIT_A5 NCIT_C82600 @default.
- NCIT_C38709 NCIT_A7 NCIT_C38910 @default.
- NCIT_C38709 NCIT_NHC0 "C38709" @default.
- NCIT_C38709 NCIT_P106 "Organic Chemical" @default.
- NCIT_C38709 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C38709 NCIT_P107 "Deslorelin" @default.
- NCIT_C38709 NCIT_P108 "Deslorelin" @default.
- NCIT_C38709 NCIT_P207 "C0083220" @default.
- NCIT_C38709 NCIT_P210 "57773-65-6" @default.
- NCIT_C38709 NCIT_P302 "Central precocious puberty" @default.
- NCIT_C38709 NCIT_P319 "TKG3I66TVE" @default.
- NCIT_C38709 NCIT_P322 "CTRP" @default.
- NCIT_C38709 NCIT_P322 "FDA" @default.
- NCIT_C38709 NCIT_P322 "GDC" @default.
- NCIT_C38709 NCIT_P325 "A substance being studied in the treatment of cancer as a way to block sex hormones made by the ovaries or testicles. It is a type of gonadotropin-releasing hormone analog." @default.
- NCIT_C38709 NCIT_P329 "357620" @default.
- NCIT_C38709 NCIT_P330 "357620" @default.
- NCIT_C38709 NCIT_P350 "C64H83N17O12" @default.
- NCIT_C38709 NCIT_P366 "Deslorelin" @default.
- NCIT_C38709 NCIT_P375 "Deslorelin" @default.
- NCIT_C38709 NCIT_P399 "357620" @default.
- NCIT_C38709 normalizedInformationContent "100" @default.
- NCIT_C38709 referenceCount "1" @default.
- NCIT_C38709 hasExactSynonym "6-D-Tryptophan-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor (Swine)" @default.
- NCIT_C38709 hasExactSynonym "DESLORELIN" @default.
- NCIT_C38709 hasExactSynonym "Deslorelin" @default.
- NCIT_C38709 hasExactSynonym "Ovuplant" @default.
- NCIT_C38709 hasExactSynonym "deslorelin" @default.
- NCIT_C38709 inSubset NCIT_C116977 @default.
- NCIT_C38709 inSubset NCIT_C116978 @default.
- NCIT_C38709 inSubset NCIT_C128784 @default.
- NCIT_C38709 inSubset NCIT_C157711 @default.
- NCIT_C38709 inSubset NCIT_C157712 @default.
- NCIT_C38709 inSubset NCIT_C176424 @default.
- NCIT_C38709 inSubset NCIT_C177537 @default.
- NCIT_C38709 inSubset NCIT_C63923 @default.
- NCIT_C38709 type Class @default.
- NCIT_C38709 isDefinedBy ncit.owl @default.
- NCIT_C38709 label "Deslorelin" @default.
- NCIT_C38709 subClassOf NCIT_C147908 @default.
- NCIT_C38709 subClassOf NCIT_C1908 @default.
- NCIT_C38709 subClassOf NCIT_C1909 @default.
- NCIT_C38709 subClassOf NCIT_C1910 @default.
- NCIT_C38709 subClassOf NCIT_C38709 @default.
- NCIT_C38709 subClassOf NCIT_C548 @default.