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- NCIT_C38797 NCIT_NHC0 "C38797" @default.
- NCIT_C38797 NCIT_P106 "Functional Concept" @default.
- NCIT_C38797 NCIT_P108 "Citrate Cycle (TCA Cycle) Pathway" @default.
- NCIT_C38797 NCIT_P207 "C1516586" @default.
- NCIT_C38797 NCIT_P215 "hsa00020" @default.
- NCIT_C38797 NCIT_P325 "The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation of carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle, but contain genes for specific segments." @default.
- NCIT_C38797 NCIT_P366 "Citrate_Cycle_TCA_Cycle_Pathway" @default.
- NCIT_C38797 normalizedInformationContent "80.516169887777039" @default.
- NCIT_C38797 referenceCount "19" @default.
- NCIT_C38797 hasExactSynonym "Citrate Cycle (TCA Cycle) Pathway" @default.
- NCIT_C38797 hasExactSynonym "Citrate Cycle (TCA cycle)" @default.
- NCIT_C38797 type Class @default.
- NCIT_C38797 isDefinedBy ncit.owl @default.
- NCIT_C38797 label "Citrate Cycle (TCA Cycle) Pathway" @default.
- NCIT_C38797 subClassOf NCIT_C18611 @default.
- NCIT_C38797 subClassOf NCIT_C20633 @default.
- NCIT_C38797 subClassOf NCIT_C38797 @default.
- NCIT_C38797 subClassOf NCIT_C39726 @default.