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- NCIT_C38910 IAO_0000115 "Gonadotropin-releasing hormone receptor (328 aa, ~38 kDa) is encoded by the human GNRHR gene. This protein is involved in the regulation of pituitary hormone release and G protein-coupled receptor signaling." @default.
- NCIT_C38910 NCIT_NHC0 "C38910" @default.
- NCIT_C38910 NCIT_P100 "138850" @default.
- NCIT_C38910 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C38910 NCIT_P106 "Receptor" @default.
- NCIT_C38910 NCIT_P107 "Gonadotropin-Releasing Hormone Receptor" @default.
- NCIT_C38910 NCIT_P108 "Gonadotropin-Releasing Hormone Receptor" @default.
- NCIT_C38910 NCIT_P207 "C0034811" @default.
- NCIT_C38910 NCIT_P322 "CTRP" @default.
- NCIT_C38910 NCIT_P366 "Gonadotropin-Releasing_Hormone_Receptor" @default.
- NCIT_C38910 NCIT_P93 "P30968" @default.
- NCIT_C38910 NCIT_P98 "Expressed as 2 alternative isoforms in pituitary, ovary, testis, breast, and prostate by human GNRHR Gene (GPCR1 Family), Gonadotropin-Releasing Hormone Receptor is a cell surface G protein-coupled 7-transmembrane-domain receptor that transduces signals from hypothalamic decapeptide GNRH by association with G proteins that activate a calcium-phosphatidylinositol second messenger system. A neuroregulator of reproduction, the primary site of GNRH action is pituitary gonadotropes, which express GNRH receptors that modulate synthesis and secretion of gonadotropic hormones LH and FSH, which regulate gametogenic and hormonal functions of gonads. GNRHR Isoform 2 may act as an inhibitor of GNRHR signaling." @default.
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- NCIT_C38910 normalizedInformationContent "84.76342111748103" @default.
- NCIT_C38910 referenceCount "10" @default.
- NCIT_C38910 hasExactSynonym "GNRHR" @default.
- NCIT_C38910 hasExactSynonym "GnRH Receptor" @default.
- NCIT_C38910 hasExactSynonym "GnRH-R" @default.
- NCIT_C38910 hasExactSynonym "Gonadotropin-Releasing Hormone (Type 1) Receptor 1" @default.
- NCIT_C38910 hasExactSynonym "Gonadotropin-Releasing Hormone Receptor" @default.
- NCIT_C38910 hasExactSynonym "LHRH-R" @default.
- NCIT_C38910 hasExactSynonym "LHRHR" @default.
- NCIT_C38910 hasExactSynonym "LRHR Receptor" @default.
- NCIT_C38910 hasExactSynonym "Leutinizing Hormone Releasing Hormone Receptor" @default.
- NCIT_C38910 hasExactSynonym "Leutinizing Hormone-Releasing Hormone Receptor" @default.
- NCIT_C38910 hasExactSynonym "Leutinizing-Releasing Hormone Receptor" @default.
- NCIT_C38910 hasExactSynonym "Luliberin Receptor" @default.
- NCIT_C38910 hasExactSynonym "Type I GnRH Receptor" @default.
- NCIT_C38910 inSubset NCIT_C116977 @default.
- NCIT_C38910 inSubset NCIT_C142799 @default.
- NCIT_C38910 inSubset NCIT_C142800 @default.
- NCIT_C38910 type Class @default.
- NCIT_C38910 isDefinedBy ncit.owl @default.
- NCIT_C38910 label "Gonadotropin-Releasing Hormone Receptor" @default.
- NCIT_C38910 subClassOf NCIT_C17021 @default.
- NCIT_C38910 subClassOf NCIT_C17728 @default.
- NCIT_C38910 subClassOf NCIT_C18106 @default.
- NCIT_C38910 subClassOf NCIT_C18239 @default.
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- NCIT_C38910 subClassOf NCIT_C26548 @default.
- NCIT_C38910 subClassOf NCIT_C38910 @default.
- NCIT_C38910 equivalentClass B0d6e260a9fffc9bc683eea342b404d1b @default.
- NCIT_C38910 equivalentClass Bc5dacd488cbe47ca2a1cfc18c189523b @default.