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- NCIT_C38958 IAO_0000115 "Heterotrimeric Elongation Factor 1 (containing alpha/beta/gamma or alpha/delta/gamma subunits) is responsible for delivery of aminoacyl tRNAs to the ribosome. Containing domains that bind guanine nucleotides, 80S ribosomes, and aminoacyl-tRNAs, the alpha EF-1 subunit interacts with beta/delta subunits and mediates delivery and GTP-dependent binding of aminoacyl-tRNAs to the 80S ribosome A-site. Homologous beta and delta subunits (guanine nucleotide exchange factors) stimulate GDP/GTP exchange bound to EF-1-alpha; phosphorylation affects the GDP/GTP exchange rate. The conserved gamma subunit contains an EEF1G domain and an N-terminal GST domain that may be involved in regulating EF-1 multisubunit assembly and anchorage to other cellular components. (NCI)" @default.
- NCIT_C38958 NCIT_NHC0 "C38958" @default.
- NCIT_C38958 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C38958 NCIT_P107 "Elongation Factor 1" @default.
- NCIT_C38958 NCIT_P108 "Elongation Factor 1" @default.
- NCIT_C38958 NCIT_P207 "C0059036" @default.
- NCIT_C38958 NCIT_P322 "CTRP" @default.
- NCIT_C38958 NCIT_P366 "Elongation_Factor-1" @default.
- NCIT_C38958 NCIT_R52 NCIT_C16554 @default.
- NCIT_C38958 NCIT_R52 NCIT_C16650 @default.
- NCIT_C38958 NCIT_R52 NCIT_C16701 @default.
- NCIT_C38958 NCIT_R52 NCIT_C17021 @default.
- NCIT_C38958 NCIT_R52 NCIT_C17494 @default.
- NCIT_C38958 NCIT_R52 NCIT_C18515 @default.
- NCIT_C38958 NCIT_R52 NCIT_C20027 @default.
- NCIT_C38958 NCIT_R52 NCIT_C26548 @default.
- NCIT_C38958 NCIT_R52 NCIT_C38576 @default.
- NCIT_C38958 NCIT_R53 NCIT_C17702 @default.
- NCIT_C38958 NCIT_R53 NCIT_C17710 @default.
- NCIT_C38958 NCIT_R53 NCIT_C17828 @default.
- NCIT_C38958 NCIT_R53 NCIT_C18103 @default.
- NCIT_C38958 NCIT_R53 NCIT_C19536 @default.
- NCIT_C38958 NCIT_R53 NCIT_C28498 @default.
- NCIT_C38958 normalizedInformationContent "88.143637090998837" @default.
- NCIT_C38958 referenceCount "6" @default.
- NCIT_C38958 hasExactSynonym "E-F1" @default.
- NCIT_C38958 hasExactSynonym "EEF1" @default.
- NCIT_C38958 hasExactSynonym "Elongation Factor 1" @default.
- NCIT_C38958 hasExactSynonym "Elongation Factor-1" @default.
- NCIT_C38958 hasExactSynonym "Eukaryotic Elongation Factor 1" @default.
- NCIT_C38958 hasExactSynonym "Eukaryotic Translation Elongation Factor 1" @default.
- NCIT_C38958 hasExactSynonym "eEF-1" @default.
- NCIT_C38958 inSubset NCIT_C116977 @default.
- NCIT_C38958 inSubset NCIT_C142799 @default.
- NCIT_C38958 inSubset NCIT_C142800 @default.
- NCIT_C38958 type Class @default.
- NCIT_C38958 isDefinedBy ncit.owl @default.
- NCIT_C38958 label "Elongation Factor 1" @default.
- NCIT_C38958 subClassOf B2348e897f80deb44045f9607e7430307 @default.
- NCIT_C38958 subClassOf B3490f7549c9a8ebbc2abfb0c1dd71a91 @default.
- NCIT_C38958 subClassOf B3ebfe9375720e6e85314183373138508 @default.
- NCIT_C38958 subClassOf B4d45b73b661f808821aa346bd2c09161 @default.
- NCIT_C38958 subClassOf B8362769d0b7f18e18cfa169910c9ac7b @default.
- NCIT_C38958 subClassOf Bbf1523ccedad735108122507f43471f8 @default.
- NCIT_C38958 subClassOf Bccab06fab7e136f7e098eaccb1619eb1 @default.
- NCIT_C38958 subClassOf Be84818803de69de625eefe166d7513d7 @default.
- NCIT_C38958 subClassOf NCIT_C21176 @default.
- NCIT_C38958 subClassOf NCIT_C26548 @default.
- NCIT_C38958 subClassOf NCIT_C38958 @default.