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- NCIT_C38972 NCIT_NHC0 "C38972" @default.
- NCIT_C38972 NCIT_P106 "Functional Concept" @default.
- NCIT_C38972 NCIT_P108 "AHR Signal Transduction Pathway" @default.
- NCIT_C38972 NCIT_P207 "C1510689" @default.
- NCIT_C38972 NCIT_P216 "h_acrPathway" @default.
- NCIT_C38972 NCIT_P325 "The Ah receptor, bHLH/PAS transcription factor, upon binding of an agonist such as 2,3,7,8-tetrachlorodibenzo-p-dioxin translocates into the nucleus and heterodimerizes with the transcription factor ARNT. The Ah receptor/ARNT heterodimer binds to dioxin-responsive elements and alters expression of a number of genes including; CYP1A1, CYP1A2, CYP1B1, and NAD(P)H quinone oxidoreductase. The inactive form of the Ah receptor exists in the cytoplasm as a tetrameric complex composed of the ligand binding subunit, a dimer of the 90-kDa heat shock protein, and X-associated protein 2 (also referred to as AIP or ARA9). (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C38972 NCIT_P366 "AHR_Signal_Transduction_Pathway" @default.
- NCIT_C38972 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C38972 normalizedInformationContent "85.460608731874885" @default.
- NCIT_C38972 referenceCount "9" @default.
- NCIT_C38972 hasExactSynonym "AHR Signal Transduction Pathway" @default.
- NCIT_C38972 hasExactSynonym "Ahr Signal Transduction Pathway" @default.
- NCIT_C38972 type Class @default.
- NCIT_C38972 isDefinedBy ncit.owl @default.
- NCIT_C38972 label "AHR Signal Transduction Pathway" @default.
- NCIT_C38972 subClassOf NCIT_C17132 @default.
- NCIT_C38972 subClassOf NCIT_C20633 @default.
- NCIT_C38972 subClassOf NCIT_C38972 @default.