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- NCIT_C38993 NCIT_NHC0 "C38993" @default.
- NCIT_C38993 NCIT_P106 "Functional Concept" @default.
- NCIT_C38993 NCIT_P108 "Arginine, Histidine, Glutamate, Glutamine, and Proline Degradation Pathway" @default.
- NCIT_C38993 NCIT_P207 "C1510937" @default.
- NCIT_C38993 NCIT_P216 "h_argininecPathway" @default.
- NCIT_C38993 NCIT_P325 "Glutamine is converted to glutamate by glutaminase, or several other enzymes, by the removal of the amide nitrogen. Proline is first converted to a Schiff base and then converted by hydrolysis to glutamate-5-semialdehyde. All of these changes occur on the same carbon. Arginine and histidine contain 5 adjacent carbons and a sixth carbon attached through a nitrogen atom. The catabolism of these amino acids is thus slightly more complicated than glutamine or proline. Arginine is converted to ornithine and urea. Ornithine is further transaminated to produce glutamate-5-semialdehyde. Glutamate-5-semialdehyde is converted to glutamate. Tetrahydrofolate is the cofactor in the final step converting histidine to glutamate. Transamination or deamination of glutamate produces a-ketoglutarate which feeds into the citric acid cycle. (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C38993 NCIT_P366 "Arginine_Histidine_Glutamate_Glutamine_and_Proline_Degradation_Pathway" @default.
- NCIT_C38993 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C38993 normalizedInformationContent "100" @default.
- NCIT_C38993 referenceCount "1" @default.
- NCIT_C38993 hasExactSynonym "Arginine, Histidine, Glutamate, Glutamine, and Proline Degradation Pathway" @default.
- NCIT_C38993 hasExactSynonym "Catabolic Pathways for Arginine, Histidine, Glutamate, Glutamine, and Proline" @default.
- NCIT_C38993 type Class @default.
- NCIT_C38993 isDefinedBy ncit.owl @default.
- NCIT_C38993 label "Arginine, Histidine, Glutamate, Glutamine, and Proline Degradation Pathway" @default.
- NCIT_C38993 subClassOf NCIT_C18611 @default.
- NCIT_C38993 subClassOf NCIT_C20633 @default.
- NCIT_C38993 subClassOf NCIT_C38993 @default.
- NCIT_C38993 subClassOf NCIT_C39730 @default.