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- NCIT_C39153 NCIT_NHC0 "C39153" @default.
- NCIT_C39153 NCIT_P106 "Functional Concept" @default.
- NCIT_C39153 NCIT_P108 "Antigen Presentation Pathway" @default.
- NCIT_C39153 NCIT_P207 "C1516014" @default.
- NCIT_C39153 NCIT_P216 "h_mhcPathway" @default.
- NCIT_C39153 NCIT_P325 "Invariant chain (Ii) associates with newly synthesized class II molecules in the endoplasmic reticulum (ER), an interaction that has been shown to interfere with peptide binding to class II molecules. The class II-associated invariant chain peptide (CLIP) region (residues 81-104) of Ii is believed to mediate this inhibition by engaging the binding domain of class II like an antigenic peptide. Together, these findings have given rise to a model in which CLIP association with the class II groove acts to prevent inappropriate presentation of peptides imported into the ER for association with major histocompatibility complex class I molecules. (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C39153 NCIT_P366 "Antigen_Presentation_Pathway" @default.
- NCIT_C39153 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C39153 normalizedInformationContent "81.252167948509552" @default.
- NCIT_C39153 referenceCount "17" @default.
- NCIT_C39153 hasExactSynonym "Antigen Presentation Pathway" @default.
- NCIT_C39153 hasExactSynonym "Antigen Processing and Presentation" @default.
- NCIT_C39153 type Class @default.
- NCIT_C39153 isDefinedBy ncit.owl @default.
- NCIT_C39153 label "Antigen Presentation Pathway" @default.
- NCIT_C39153 subClassOf NCIT_C19779 @default.
- NCIT_C39153 subClassOf NCIT_C20633 @default.
- NCIT_C39153 subClassOf NCIT_C39153 @default.
- NCIT_C39153 subClassOf NCIT_C39698 @default.