Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C39191> ?p ?o ?g. }
Showing items 1 to 18 of
18
with 100 items per page.
- NCIT_C39191 NCIT_NHC0 "C39191" @default.
- NCIT_C39191 NCIT_P106 "Functional Concept" @default.
- NCIT_C39191 NCIT_P108 "Platelet Amyloid Precursor Protein Pathway" @default.
- NCIT_C39191 NCIT_P207 "C1514160" @default.
- NCIT_C39191 NCIT_P216 "h_plateletAppPathway" @default.
- NCIT_C39191 NCIT_P325 "The amyloid-beta peptide (Ab), a proteolytic fragment of amyloid precursor protein (APP), is the major component of senile plaques, the hallmark of Alzheimer's disease. Platelets contain both APP and Ab and probably contribute greater than 90% of circulating APP. The soluble APP is the major inhibitor of coagulation factors IXa and XIa, and platelet aggregation. Agonists such as ADP, thrombin, epinephrine and collagen activate the release of APP and plasminogen activator inhibitor I (an important regulator of coagulation) from platelet storage granules. These important molecules released from platelets are key regulators of hemostasis, the physiologic arrest of hemorrhage at site of vascular leakage. (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C39191 NCIT_P366 "Platelet_Amyloid_Precursor_Protein_Pathway" @default.
- NCIT_C39191 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C39191 normalizedInformationContent "81.252167948509552" @default.
- NCIT_C39191 referenceCount "17" @default.
- NCIT_C39191 hasExactSynonym "Platelet Amyloid Precursor Protein Pathway" @default.
- NCIT_C39191 type Class @default.
- NCIT_C39191 isDefinedBy ncit.owl @default.
- NCIT_C39191 label "Platelet Amyloid Precursor Protein Pathway" @default.
- NCIT_C39191 subClassOf NCIT_C19779 @default.
- NCIT_C39191 subClassOf NCIT_C20633 @default.
- NCIT_C39191 subClassOf NCIT_C39191 @default.
- NCIT_C39191 subClassOf NCIT_C91822 @default.