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- NCIT_C39215 NCIT_NHC0 "C39215" @default.
- NCIT_C39215 NCIT_P106 "Functional Concept" @default.
- NCIT_C39215 NCIT_P108 "RAR and RXR Degradation Pathway" @default.
- NCIT_C39215 NCIT_P207 "C1514637" @default.
- NCIT_C39215 NCIT_P216 "h_rarPathway" @default.
- NCIT_C39215 NCIT_P325 "Once retinoids are bound by the RAR/RXR heterodimer they became transcriptional activated. As a consequence they are degraded by the proteasome. Phosphorylation in the activation domain one (AF1) and presence of the activation domain 2 (AF2) trigger the ubiquitination of the receptors. Moreover, heterodimerization of RAR and RXR accelerate degradation of the receptors. (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C39215 NCIT_P366 "RAR_and_RXR_Degradation_Pathway" @default.
- NCIT_C39215 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C39215 normalizedInformationContent "85.460608731874885" @default.
- NCIT_C39215 referenceCount "9" @default.
- NCIT_C39215 hasExactSynonym "Degradation of the RAR and RXR by the proteasome" @default.
- NCIT_C39215 hasExactSynonym "RAR and RXR Degradation Pathway" @default.
- NCIT_C39215 type Class @default.
- NCIT_C39215 isDefinedBy ncit.owl @default.
- NCIT_C39215 label "RAR and RXR Degradation Pathway" @default.
- NCIT_C39215 subClassOf NCIT_C18611 @default.
- NCIT_C39215 subClassOf NCIT_C20633 @default.
- NCIT_C39215 subClassOf NCIT_C39215 @default.
- NCIT_C39215 subClassOf NCIT_C39702 @default.