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- NCIT_C39216 NCIT_NHC0 "C39216" @default.
- NCIT_C39216 NCIT_P106 "Functional Concept" @default.
- NCIT_C39216 NCIT_P108 "Chromatin Remodeling Complex and Coactivator Pathway" @default.
- NCIT_C39216 NCIT_P207 "C1516510" @default.
- NCIT_C39216 NCIT_P216 "h_rarrxrPathway" @default.
- NCIT_C39216 NCIT_P325 "RXR and RAR are nuclear receptors that bind either all trans retinoic (tRA) or 9cis retinoic acid (9cisRA). In the absence of ligand corepressors with histone deacetylase activity are bound to the RAR/RXR heterodimer and suppress transcription. Once they bind retinoic acid a conformational change in the receptors cause the dissociation of the corepressors and the binding of coactivators with histone acetylase activity. Following ligand binding by the heterodimer the receptors and proteins in the basal transcription machinery (like TBP and TAF135) are degraded by the proteasome. (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C39216 NCIT_P366 "Chromatin_Remodeling_Complex_and_Coactivator_Pathway" @default.
- NCIT_C39216 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C39216 normalizedInformationContent "75.929502612838462" @default.
- NCIT_C39216 referenceCount "38" @default.
- NCIT_C39216 hasExactSynonym "Chromatin Remodeling Complex and Coactivator Pathway" @default.
- NCIT_C39216 hasExactSynonym "Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells" @default.
- NCIT_C39216 type Class @default.
- NCIT_C39216 isDefinedBy ncit.owl @default.
- NCIT_C39216 label "Chromatin Remodeling Complex and Coactivator Pathway" @default.
- NCIT_C39216 subClassOf NCIT_C19779 @default.
- NCIT_C39216 subClassOf NCIT_C20633 @default.
- NCIT_C39216 subClassOf NCIT_C39216 @default.