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- NCIT_C394 IAO_0000115 "Any synthetic therapeutic agent which is chemically identical to or similar to the endogenous human corticotropin-releasing factor (hCRF). Synthesized in the hypothalamus, hCRF stimulates the anterior pituitary gland to secrete adrenocorticotropic hormone (ACTH). In cerebral edema, hCRF acts by impeding the flow of fluid from blood vessels into brain tissue, thereby decreasing edema and stabilizing intracranial pressure. This agent possesses anti-edema properties independent of adrenal gland function. (NCI05)" @default.
- NCIT_C394 NCIT_NHC0 "C394" @default.
- NCIT_C394 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C394 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C394 NCIT_P108 "Therapeutic Corticotropin-Releasing Factor" @default.
- NCIT_C394 NCIT_P208 "CL324578" @default.
- NCIT_C394 NCIT_P210 "86784-80-7" @default.
- NCIT_C394 NCIT_P319 "305OE8862Y" @default.
- NCIT_C394 NCIT_P322 "FDA" @default.
- NCIT_C394 NCIT_P350 "C208H344N60O63S2" @default.
- NCIT_C394 NCIT_P366 "Therapeutic_Corticotropin_Releasing_Factor" @default.
- NCIT_C394 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C394 referenceCount "4" @default.
- NCIT_C394 hasExactSynonym "CFR" @default.
- NCIT_C394 hasExactSynonym "CORTICORELIN" @default.
- NCIT_C394 hasExactSynonym "Corticoliberin" @default.
- NCIT_C394 hasExactSynonym "Corticorelin" @default.
- NCIT_C394 hasExactSynonym "Recombinant Human Corticotropin Releasing Factor" @default.
- NCIT_C394 hasExactSynonym "Therapeutic Corticotropin-Releasing Factor" @default.
- NCIT_C394 inSubset NCIT_C63923 @default.
- NCIT_C394 type Class @default.
- NCIT_C394 isDefinedBy ncit.owl @default.
- NCIT_C394 label "Therapeutic Corticotropin-Releasing Factor" @default.
- NCIT_C394 subClassOf NCIT_C147908 @default.
- NCIT_C394 subClassOf NCIT_C1908 @default.
- NCIT_C394 subClassOf NCIT_C1909 @default.
- NCIT_C394 subClassOf NCIT_C394 @default.
- NCIT_C394 subClassOf NCIT_C548 @default.