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- NCIT_C40684 IAO_0000115 "Complement Stabilization inhibits conjugation, transport, oxidation, or proteolysis of complement system proteins; sequentially interacting serum proteins (some serine proteases), their receptors, and related regulatory proteins. Activated by cell-surface bound antibody, immune complexes, or a microbial membrane carbohydrate, complex complement cascades (classical or properdin pathway) generate Membrane Attack Complex, which creates target cell wall pores and lysis. The complement system also plays a role in antibody-dependent cytolysis, anaphylaxis, phagocytosis, opsonization, chemotaxis, and hemolysis." @default.
- NCIT_C40684 NCIT_NHC0 "C40684" @default.
- NCIT_C40684 NCIT_P106 "Physiologic Function" @default.
- NCIT_C40684 NCIT_P108 "Negative Regulation of Degradation of Complement" @default.
- NCIT_C40684 NCIT_P207 "C1516745" @default.
- NCIT_C40684 NCIT_P366 "Complement_Stabilization" @default.
- NCIT_C40684 NCIT_R35 NCIT_C17710 @default.
- NCIT_C40684 NCIT_R35 NCIT_C17828 @default.
- NCIT_C40684 NCIT_R35 NCIT_C28498 @default.
- NCIT_C40684 normalizedInformationContent "100" @default.
- NCIT_C40684 referenceCount "1" @default.
- NCIT_C40684 hasExactSynonym "Complement Stabilization" @default.
- NCIT_C40684 hasExactSynonym "Negative Regulation of Degradation of Complement" @default.
- NCIT_C40684 type Class @default.
- NCIT_C40684 isDefinedBy ncit.owl @default.
- NCIT_C40684 label "Negative Regulation of Degradation of Complement" @default.
- NCIT_C40684 subClassOf NCIT_C17710 @default.
- NCIT_C40684 subClassOf NCIT_C17828 @default.
- NCIT_C40684 subClassOf NCIT_C18104 @default.
- NCIT_C40684 subClassOf NCIT_C19406 @default.
- NCIT_C40684 subClassOf NCIT_C19536 @default.
- NCIT_C40684 subClassOf NCIT_C19903 @default.
- NCIT_C40684 subClassOf NCIT_C19986 @default.
- NCIT_C40684 subClassOf NCIT_C21198 @default.
- NCIT_C40684 subClassOf NCIT_C28498 @default.
- NCIT_C40684 subClassOf NCIT_C40677 @default.
- NCIT_C40684 subClassOf NCIT_C40684 @default.
- NCIT_C40684 subClassOf NCIT_C61559 @default.