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- NCIT_C412 IAO_0000115 "A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces parvulus. Dactinomycin intercalates between adjacent guanine-cytosine base pairs, blocking the transcription of DNA by RNA polymerase; it also causes single-strand DNA breaks, possibly via a free-radical intermediate or an interaction with topoisomerase II. (NCI04)" @default.
- NCIT_C412 NCIT_A32 NCIT_C1909 @default.
- NCIT_C412 NCIT_A33 NCIT_C274 @default.
- NCIT_C412 NCIT_NHC0 "C412" @default.
- NCIT_C412 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C412 NCIT_P106 "Antibiotic" @default.
- NCIT_C412 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C412 NCIT_P107 "Dactinomycin" @default.
- NCIT_C412 NCIT_P108 "Dactinomycin" @default.
- NCIT_C412 NCIT_P175 "3053" @default.
- NCIT_C412 NCIT_P207 "C0010934" @default.
- NCIT_C412 NCIT_P210 "50-76-0" @default.
- NCIT_C412 NCIT_P302 "Wilms' tumor; rhabdomyosarcoma; Ewing's sarcoma; testicular cancer; gestational trophoblastic neoplasia; choriocarcinoma; melanoma; neuroblastoma; retinoblastoma; uterine sarcomas; Kaposi's sarcoma; sarcoma botryoides; soft tissue sarcoma." @default.
- NCIT_C412 NCIT_P319 "1CC1JFE158" @default.
- NCIT_C412 NCIT_P322 "CTRP" @default.
- NCIT_C412 NCIT_P322 "FDA" @default.
- NCIT_C412 NCIT_P322 "GDC" @default.
- NCIT_C412 NCIT_P322 "PCDC" @default.
- NCIT_C412 NCIT_P325 "An anticancer drug that is a type of antitumor antibiotic." @default.
- NCIT_C412 NCIT_P329 "39675" @default.
- NCIT_C412 NCIT_P330 "39675" @default.
- NCIT_C412 NCIT_P350 "C62H86N12O16" @default.
- NCIT_C412 NCIT_P366 "Dactinomycin" @default.
- NCIT_C412 NCIT_P368 "CHEBI:27666" @default.
- NCIT_C412 NCIT_P375 "Dactinomycin" @default.
- NCIT_C412 NCIT_P399 "39675" @default.
- NCIT_C412 normalizedInformationContent "74.52294908827146" @default.
- NCIT_C412 referenceCount "47" @default.
- NCIT_C412 hasExactSynonym "2-bis[Cyclo(N-methyl-L-valyl-sarcosyl-L-prolyl-D-valyl-L-threonyl)]-1,9 dimethyl-4,6 3H-phenoxazinone-3" @default.
- NCIT_C412 hasExactSynonym "ACTINOMYCIN D" @default.
- NCIT_C412 hasExactSynonym "Actinomycin A IV" @default.
- NCIT_C412 hasExactSynonym "Actinomycin C1" @default.
- NCIT_C412 hasExactSynonym "Actinomycin D" @default.
- NCIT_C412 hasExactSynonym "Actinomycin I1" @default.
- NCIT_C412 hasExactSynonym "Actinomycin IV" @default.
- NCIT_C412 hasExactSynonym "Actinomycin X 1" @default.
- NCIT_C412 hasExactSynonym "Actinomycin-[thr-val-pro-sar-meval]" @default.
- NCIT_C412 hasExactSynonym "Cosmegen" @default.
- NCIT_C412 hasExactSynonym "DACT" @default.
- NCIT_C412 hasExactSynonym "DACTINOMYCIN" @default.
- NCIT_C412 hasExactSynonym "Dactinomycin" @default.
- NCIT_C412 hasExactSynonym "Dactinomycine" @default.
- NCIT_C412 hasExactSynonym "Lyovac Cosmegen" @default.
- NCIT_C412 hasExactSynonym "Lyovac cosmegen" @default.
- NCIT_C412 hasExactSynonym "Meractinomycin" @default.
- NCIT_C412 hasExactSynonym "dactinomycin" @default.
- NCIT_C412 inSubset NCIT_C116977 @default.
- NCIT_C412 inSubset NCIT_C116978 @default.
- NCIT_C412 inSubset NCIT_C128784 @default.
- NCIT_C412 inSubset NCIT_C157711 @default.
- NCIT_C412 inSubset NCIT_C157712 @default.
- NCIT_C412 inSubset NCIT_C176424 @default.
- NCIT_C412 inSubset NCIT_C177383 @default.
- NCIT_C412 inSubset NCIT_C177406 @default.
- NCIT_C412 inSubset NCIT_C177537 @default.
- NCIT_C412 inSubset NCIT_C63923 @default.
- NCIT_C412 type Class @default.
- NCIT_C412 isDefinedBy ncit.owl @default.
- NCIT_C412 label "Dactinomycin" @default.
- NCIT_C412 subClassOf NCIT_C186664 @default.
- NCIT_C412 subClassOf NCIT_C1908 @default.
- NCIT_C412 subClassOf NCIT_C1909 @default.
- NCIT_C412 subClassOf NCIT_C204 @default.
- NCIT_C412 subClassOf NCIT_C2115 @default.
- NCIT_C412 subClassOf NCIT_C2161 @default.
- NCIT_C412 subClassOf NCIT_C259 @default.
- NCIT_C412 subClassOf NCIT_C274 @default.
- NCIT_C412 subClassOf NCIT_C2842 @default.
- NCIT_C412 subClassOf NCIT_C412 @default.