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- NCIT_C428 IAO_0000115 "A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth muscle, thereby stabilizing the membrane action potential and preventing vascular smooth muscle contraction; this results in peripheral vasodilatation and decreases in peripheral vascular resistance. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells." @default.
- NCIT_C428 NCIT_NHC0 "C428" @default.
- NCIT_C428 NCIT_P106 "Organic Chemical" @default.
- NCIT_C428 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C428 NCIT_P108 "Diazoxide" @default.
- NCIT_C428 NCIT_P175 "64198" @default.
- NCIT_C428 NCIT_P175 "76130" @default.
- NCIT_C428 NCIT_P207 "C0012022" @default.
- NCIT_C428 NCIT_P210 "364-98-7" @default.
- NCIT_C428 NCIT_P302 "Malignant Hypertension" @default.
- NCIT_C428 NCIT_P319 "O5CB12L4FN" @default.
- NCIT_C428 NCIT_P322 "FDA" @default.
- NCIT_C428 NCIT_P329 "39290" @default.
- NCIT_C428 NCIT_P330 "39290" @default.
- NCIT_C428 NCIT_P350 "C8H7ClN2O2S" @default.
- NCIT_C428 NCIT_P366 "Diazoxide" @default.
- NCIT_C428 NCIT_P368 "CHEBI:4495" @default.
- NCIT_C428 NCIT_P399 "39290" @default.
- NCIT_C428 normalizedInformationContent "100" @default.
- NCIT_C428 referenceCount "1" @default.
- NCIT_C428 hasExactSynonym "3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-Dioxide" @default.
- NCIT_C428 hasExactSynonym "DIAZOXIDE" @default.
- NCIT_C428 hasExactSynonym "Diazoxide" @default.
- NCIT_C428 hasExactSynonym "Proglycem" @default.
- NCIT_C428 hasExactSynonym "SRG-95213" @default.
- NCIT_C428 inSubset NCIT_C176424 @default.
- NCIT_C428 inSubset NCIT_C63923 @default.
- NCIT_C428 type Class @default.
- NCIT_C428 isDefinedBy ncit.owl @default.
- NCIT_C428 label "Diazoxide" @default.
- NCIT_C428 subClassOf NCIT_C1908 @default.
- NCIT_C428 subClassOf NCIT_C1909 @default.
- NCIT_C428 subClassOf NCIT_C29707 @default.
- NCIT_C428 subClassOf NCIT_C428 @default.
- NCIT_C428 subClassOf NCIT_C78274 @default.