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- NCIT_C44435 IAO_0000115 "The hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen." @default.
- NCIT_C44435 NCIT_A6 NCIT_C62065 @default.
- NCIT_C44435 NCIT_NHC0 "C44435" @default.
- NCIT_C44435 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C44435 NCIT_P108 "Phenoxybenzamine Hydrochloride" @default.
- NCIT_C44435 NCIT_P175 "37448" @default.
- NCIT_C44435 NCIT_P207 "C0701367" @default.
- NCIT_C44435 NCIT_P210 "63-92-3" @default.
- NCIT_C44435 NCIT_P319 "X1IEG24OHL" @default.
- NCIT_C44435 NCIT_P322 "FDA" @default.
- NCIT_C44435 NCIT_P329 "703206" @default.
- NCIT_C44435 NCIT_P330 "703206" @default.
- NCIT_C44435 NCIT_P350 "C18H22ClNO.HCl" @default.
- NCIT_C44435 NCIT_P366 "Phenoxybenzamine" @default.
- NCIT_C44435 NCIT_P399 "703206" @default.
- NCIT_C44435 normalizedInformationContent "100" @default.
- NCIT_C44435 referenceCount "1" @default.
- NCIT_C44435 hasExactSynonym "Dibenzyline" @default.
- NCIT_C44435 hasExactSynonym "N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzenemethanamine Hydrochloride" @default.
- NCIT_C44435 hasExactSynonym "PHENOXYBENZAMINE HYDROCHLORIDE" @default.
- NCIT_C44435 hasExactSynonym "Phenoxybenzamine Hydrochloride" @default.
- NCIT_C44435 inSubset NCIT_C176424 @default.
- NCIT_C44435 inSubset NCIT_C63923 @default.
- NCIT_C44435 type Class @default.
- NCIT_C44435 isDefinedBy ncit.owl @default.
- NCIT_C44435 label "Phenoxybenzamine Hydrochloride" @default.
- NCIT_C44435 subClassOf NCIT_C1908 @default.
- NCIT_C44435 subClassOf NCIT_C1909 @default.
- NCIT_C44435 subClassOf NCIT_C29713 @default.
- NCIT_C44435 subClassOf NCIT_C29747 @default.
- NCIT_C44435 subClassOf NCIT_C44435 @default.
- NCIT_C44435 subClassOf NCIT_C72900 @default.
- NCIT_C44435 subClassOf NCIT_C78272 @default.