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- NCIT_C45438 IAO_0000115 "Programmed cell death 1 ligand 2 (273 aa, ~31 kDa) is encoded by the human PDCD1LG2 gene. This protein is involved in the modulation of both T-cell proliferation and cytokine production." @default.
- NCIT_C45438 NCIT_NHC0 "C45438" @default.
- NCIT_C45438 NCIT_P100 "605723" @default.
- NCIT_C45438 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C45438 NCIT_P107 "Programmed Cell Death 1 Ligand 2" @default.
- NCIT_C45438 NCIT_P108 "Programmed Cell Death 1 Ligand 2" @default.
- NCIT_C45438 NCIT_P207 "C0965743" @default.
- NCIT_C45438 NCIT_P322 "CTRP" @default.
- NCIT_C45438 NCIT_P366 "Programmed_Death_Ligand-2_Protein" @default.
- NCIT_C45438 NCIT_P93 "Q9BQ51" @default.
- NCIT_C45438 NCIT_P98 "Widely expressed (highest in placenta, heart, pancreas, lung, and liver) by human PDCD1LG2 Gene, 273 aa 31-kDa Programmed Death Ligand 2 Protein is 70% identical to mouse Pdl2 protein and contains a signal sequence, IgV- and IgC-like domains, a transmembrane region, and a cytoplasmic region. Gamma-interferon stimulates PDCD1LG2 expression in monocytes. The IgV domain appears to bind to PDCD1, but not to CTLA4, CD28, or ICOS. Stimulation with anti-CD3 and Pdl2, or Pdl1, inhibits proliferation of mouse T cells and cytokine production. At low anti-CD3 concentrations, mouse Pdl2 preferentially co-stimulates CD4-positive (Th1) T-cell proliferation and Ifng production." @default.
- NCIT_C45438 NCIT_R53 NCIT_C17710 @default.
- NCIT_C45438 NCIT_R53 NCIT_C17828 @default.
- NCIT_C45438 NCIT_R53 NCIT_C17937 @default.
- NCIT_C45438 NCIT_R53 NCIT_C18219 @default.
- NCIT_C45438 NCIT_R53 NCIT_C18469 @default.
- NCIT_C45438 NCIT_R53 NCIT_C18839 @default.
- NCIT_C45438 NCIT_R53 NCIT_C19986 @default.
- NCIT_C45438 NCIT_R53 NCIT_C21124 @default.
- NCIT_C45438 NCIT_R54 NCIT_C16612 @default.
- NCIT_C45438 NCIT_R54 NCIT_C25790 @default.
- NCIT_C45438 NCIT_R54 NCIT_C45437 @default.
- NCIT_C45438 normalizedInformationContent "100" @default.
- NCIT_C45438 referenceCount "1" @default.
- NCIT_C45438 hasExactSynonym "B7 Dendritic Cell Molecule" @default.
- NCIT_C45438 hasExactSynonym "B7-DC" @default.
- NCIT_C45438 hasExactSynonym "B7DC" @default.
- NCIT_C45438 hasExactSynonym "Butyrophilin B7-DC" @default.
- NCIT_C45438 hasExactSynonym "CD273 Antigen" @default.
- NCIT_C45438 hasExactSynonym "CD273" @default.
- NCIT_C45438 hasExactSynonym "PD-1 Ligand 2" @default.
- NCIT_C45438 hasExactSynonym "PD-1-Ligand 2" @default.
- NCIT_C45438 hasExactSynonym "PD-L2" @default.
- NCIT_C45438 hasExactSynonym "PD1 Ligand 2 Protein" @default.
- NCIT_C45438 hasExactSynonym "PDCD1 Ligand 2 Protein" @default.
- NCIT_C45438 hasExactSynonym "PDCD1 Ligand 2" @default.
- NCIT_C45438 hasExactSynonym "PDCD1L2" @default.
- NCIT_C45438 hasExactSynonym "PDCD1LG2" @default.
- NCIT_C45438 hasExactSynonym "PDL2" @default.
- NCIT_C45438 hasExactSynonym "Programmed Cell Death 1 Ligand 2" @default.
- NCIT_C45438 hasExactSynonym "Programmed Death Ligand 2 Protein" @default.
- NCIT_C45438 hasExactSynonym "Programmed Death Ligand 2" @default.
- NCIT_C45438 inSubset NCIT_C116977 @default.
- NCIT_C45438 inSubset NCIT_C142799 @default.
- NCIT_C45438 inSubset NCIT_C142800 @default.
- NCIT_C45438 type Class @default.
- NCIT_C45438 isDefinedBy ncit.owl @default.
- NCIT_C45438 label "Programmed Cell Death 1 Ligand 2" @default.
- NCIT_C45438 subClassOf B4b22ceb88f07872b93ef3253a2844fbb @default.
- NCIT_C45438 subClassOf B7b57d1cc10f3951da36c6d056bfe0f7f @default.
- NCIT_C45438 subClassOf B95f0f2bfa8955694f8084b69b2c202df @default.
- NCIT_C45438 subClassOf Bcdf67932ae4c45b7cd6179767141b029 @default.
- NCIT_C45438 subClassOf NCIT_C16725 @default.
- NCIT_C45438 subClassOf NCIT_C17021 @default.
- NCIT_C45438 subClassOf NCIT_C20027 @default.
- NCIT_C45438 subClassOf NCIT_C26548 @default.
- NCIT_C45438 subClassOf NCIT_C45438 @default.