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- NCIT_C455 IAO_0000115 "The hydrochloride salt form of dopamine, a monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1- and beta-1- adrenergic receptors. Mediated through myocardial beta-1-adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1-adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output." @default.
- NCIT_C455 NCIT_A6 NCIT_C62025 @default.
- NCIT_C455 NCIT_NHC0 "C455" @default.
- NCIT_C455 NCIT_P106 "Biologically Active Substance" @default.
- NCIT_C455 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C455 NCIT_P108 "Dopamine Hydrochloride" @default.
- NCIT_C455 NCIT_P175 "173182" @default.
- NCIT_C455 NCIT_P207 "C0282151" @default.
- NCIT_C455 NCIT_P210 "62-31-7" @default.
- NCIT_C455 NCIT_P319 "7L3E358N9L" @default.
- NCIT_C455 NCIT_P322 "FDA" @default.
- NCIT_C455 NCIT_P350 "C8H11NO2.HCl" @default.
- NCIT_C455 NCIT_P366 "Dopamine" @default.
- NCIT_C455 normalizedInformationContent "100" @default.
- NCIT_C455 referenceCount "1" @default.
- NCIT_C455 hasExactSynonym "DOPAMINE HYDROCHLORIDE" @default.
- NCIT_C455 hasExactSynonym "Dopamine Hydrochloride" @default.
- NCIT_C455 hasExactSynonym "Dopaminergic" @default.
- NCIT_C455 inSubset NCIT_C63923 @default.
- NCIT_C455 type Class @default.
- NCIT_C455 isDefinedBy ncit.owl @default.
- NCIT_C455 label "Dopamine Hydrochloride" @default.
- NCIT_C455 subClassOf NCIT_C1908 @default.
- NCIT_C455 subClassOf NCIT_C1909 @default.
- NCIT_C455 subClassOf NCIT_C29709 @default.
- NCIT_C455 subClassOf NCIT_C29747 @default.
- NCIT_C455 subClassOf NCIT_C455 @default.
- NCIT_C455 subClassOf NCIT_C78272 @default.
- NCIT_C455 subClassOf NCIT_C87053 @default.