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• NCIT_C45615 IAO_0000115 "Human CYP2C9*5 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*5 protein. The CYP2C9*5 allele exhibits a clinically-relevant SNP (c.1080C>G) in exon 7 that results in a D360E coding change. This alteration in the cytochrome P450 2C9*5 protein sequence increases the Km of this enzyme for (S)-warfarin, diclofenac, and lauric acid, thereby decreasing clearance of these drugs." @default.
• NCIT_C45615 NCIT_NHC0 "C45615" @default.
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• NCIT_C45615 NCIT_P107 "CYP2C9*5 Allele" @default.
• NCIT_C45615 NCIT_P108 "CYP2C9*5 Allele" @default.
• NCIT_C45615 NCIT_P171 "15289788" @default.
• NCIT_C45615 NCIT_P207 "C1707204" @default.
• NCIT_C45615 NCIT_P322 "CTRP" @default.
• NCIT_C45615 NCIT_P366 "CYP2C9_5_Allele" @default.
• NCIT_C45615 NCIT_P96 "Cytochrome P450 2C9" @default.
• NCIT_C45615 NCIT_P98 "Ethnicity Association: African American" @default.
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• NCIT_C45615 normalizedInformationContent "100" @default.
• NCIT_C45615 referenceCount "1" @default.
• NCIT_C45615 hasExactSynonym "CYP2C9*5 Allele" @default.
• NCIT_C45615 hasExactSynonym "CYP2C9*5" @default.
• NCIT_C45615 hasExactSynonym "CYP2C9, D360E" @default.
• NCIT_C45615 hasExactSynonym "CYP2C9, c.1080C>G" @default.
• NCIT_C45615 hasExactSynonym "Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*5 Allele" @default.
• NCIT_C45615 inSubset NCIT_C116977 @default.
• NCIT_C45615 inSubset NCIT_C142799 @default.
• NCIT_C45615 inSubset NCIT_C142800 @default.
• NCIT_C45615 type Class @default.
• NCIT_C45615 isDefinedBy ncit.owl @default.
• NCIT_C45615 label "CYP2C9*5 Allele" @default.
• NCIT_C45615 subClassOf B168b6ca685c38d7a8ceeaaa23f496c96 @default.
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• NCIT_C45615 subClassOf B7b6ad8e42be987d15f175a1f25b03725 @default.
• NCIT_C45615 subClassOf B8ae9b43283ba40490f708be0556a4d5e @default.

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