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- NCIT_C45682 IAO_0000115 "Expressed in liver, human CETP B2 Allele is a variant form of CETP Gene (BPI/LBP Family), which encodes Cholesterol Ester Transfer Protein, a secreted plasma protein involved in the transfer of insoluble cholesteryl esters among lipoproteins in the reverse transport of cholesterol, a vital step in normal cholesterol metabolism and homeostasis. HDL cholesterol concentration is inversely related to the risk of coronary artery disease. CETP has a central role in HDL metabolism and may affect susceptibility to atherosclerosis; defects cause CETP deficiency. CETP B2 lacks a polymorphic TaqI restriction site in intron 1, present in CETP B1. B2 individuals show lower CETP activity and concentrations and higher plasma HDL-cholesterol; the B1 variant is associated with higher CETP and lower HDL-cholesterol. Atherosclerotic progression is more prevalent in B1 subjects than B2 subjects." @default.
- NCIT_C45682 NCIT_NHC0 "C45682" @default.
- NCIT_C45682 NCIT_P100 "118470" @default.
- NCIT_C45682 NCIT_P106 "Gene or Genome" @default.
- NCIT_C45682 NCIT_P108 "CETP 2 Allele" @default.
- NCIT_C45682 NCIT_P207 "C1707125" @default.
- NCIT_C45682 NCIT_P366 "CETP_B2_Allele" @default.
- NCIT_C45682 NCIT_P96 "Cholesteryl Ester Transfer Protein" @default.
- NCIT_C45682 NCIT_R37 NCIT_C17710 @default.
- NCIT_C45682 NCIT_R37 NCIT_C17828 @default.
- NCIT_C45682 NCIT_R37 NCIT_C18219 @default.
- NCIT_C45682 NCIT_R37 NCIT_C19405 @default.
- NCIT_C45682 NCIT_R37 NCIT_C19536 @default.
- NCIT_C45682 NCIT_R37 NCIT_C19986 @default.
- NCIT_C45682 NCIT_R37 NCIT_C20139 @default.
- NCIT_C45682 NCIT_R37 NCIT_C20739 @default.
- NCIT_C45682 NCIT_R37 NCIT_C21079 @default.
- NCIT_C45682 NCIT_R37 NCIT_C21198 @default.
- NCIT_C45682 NCIT_R37 NCIT_C25989 @default.
- NCIT_C45682 NCIT_R37 NCIT_C28498 @default.
- NCIT_C45682 NCIT_R37 NCIT_C29885 @default.
- NCIT_C45682 NCIT_R41 NCIT_C14182 @default.
- NCIT_C45682 NCIT_R41 NCIT_C14225 @default.
- NCIT_C45682 NCIT_R41 NCIT_C14234 @default.
- NCIT_C45682 NCIT_R41 NCIT_C14250 @default.
- NCIT_C45682 NCIT_R41 NCIT_C14262 @default.
- NCIT_C45682 NCIT_R41 NCIT_C14282 @default.
- NCIT_C45682 NCIT_R41 NCIT_C25796 @default.
- NCIT_C45682 NCIT_R41 NCIT_C79740 @default.
- NCIT_C45682 normalizedInformationContent "100" @default.
- NCIT_C45682 referenceCount "1" @default.
- NCIT_C45682 hasExactSynonym "CETP 2 Allele" @default.
- NCIT_C45682 hasExactSynonym "CETP B2 Allele" @default.
- NCIT_C45682 hasExactSynonym "CETP B2" @default.
- NCIT_C45682 type Class @default.
- NCIT_C45682 isDefinedBy ncit.owl @default.
- NCIT_C45682 label "CETP 2 Allele" @default.
- NCIT_C45682 subClassOf NCIT_C16612 @default.
- NCIT_C45682 subClassOf NCIT_C21295 @default.
- NCIT_C45682 subClassOf NCIT_C28533 @default.
- NCIT_C45682 subClassOf NCIT_C39780 @default.
- NCIT_C45682 subClassOf NCIT_C45682 @default.