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- NCIT_C45685 IAO_0000115 "HTR2A-C Allele is a variant form of 20-kb 3-exon human HTR2A Gene (GPCR1/5HT2 Family), which encodes Serotonin 5-HT-2A Receptor, a conserved integral membrane 5-HT/serotonin receptor protein involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production by association with G proteins that activate a PI-calcium second messenger system. 5-HT is a biogenic hormone that affects specific receptors as a neurotransmitter, hormone, or mitogen. HTR2A contains several polymorphic sites. Different alleles differ in the concentration of RNA and protein product of 5HTR2A. HTR2A-C Allele contains a single-nucleotide polymorphism (102 T>C) in an intron and is expressed at a lower level than the 102 C>T allele." @default.
- NCIT_C45685 NCIT_NHC0 "C45685" @default.
- NCIT_C45685 NCIT_P100 "182135" @default.
- NCIT_C45685 NCIT_P106 "Gene or Genome" @default.
- NCIT_C45685 NCIT_P108 "HTR2A 1 Allele" @default.
- NCIT_C45685 NCIT_P207 "C1708298" @default.
- NCIT_C45685 NCIT_P366 "HTR2A-C_Allele" @default.
- NCIT_C45685 NCIT_P96 "Serotonin 5-HT-2A Receptor" @default.
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- NCIT_C45685 normalizedInformationContent "100" @default.
- NCIT_C45685 referenceCount "1" @default.
- NCIT_C45685 hasExactSynonym "5-Hydroxytryptamine (Serotonin) Receptor 2A A2 Allele" @default.
- NCIT_C45685 hasExactSynonym "HTR2A 1 Allele" @default.
- NCIT_C45685 hasExactSynonym "HTR2A A2 Allele" @default.
- NCIT_C45685 hasExactSynonym "HTR2A A2" @default.
- NCIT_C45685 hasExactSynonym "HTR2A C" @default.
- NCIT_C45685 hasExactSynonym "HTR2A, 102T>C" @default.
- NCIT_C45685 hasExactSynonym "HTR2A-C Allele" @default.
- NCIT_C45685 hasExactSynonym "HTR2A-C" @default.
- NCIT_C45685 hasExactSynonym "HTR2A: g102T>C" @default.
- NCIT_C45685 type Class @default.
- NCIT_C45685 isDefinedBy ncit.owl @default.
- NCIT_C45685 label "HTR2A 1 Allele" @default.
- NCIT_C45685 subClassOf NCIT_C16612 @default.
- NCIT_C45685 subClassOf NCIT_C20103 @default.
- NCIT_C45685 subClassOf NCIT_C20923 @default.
- NCIT_C45685 subClassOf NCIT_C21295 @default.
- NCIT_C45685 subClassOf NCIT_C39775 @default.
- NCIT_C45685 subClassOf NCIT_C45685 @default.