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- NCIT_C45873 IAO_0000115 "A fluorinated derivative of the 2-nitroimidazole etanidazole. EF5 is effective in accessing oxygen levels in tumor tissue through its adduct formation to intracellular macromolecules in the absence of oxygen. Reduction of this agent is carried out by a diverse group of enzymes in the cytoplasm, microsomes and mitochondria. Tissue hypoxia detection via EF5 has been reported in several cancers, including squamous cell carcinoma of the cervix and the head and neck, and in sarcoma." @default.
- NCIT_C45873 NCIT_NHC0 "C45873" @default.
- NCIT_C45873 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C45873 NCIT_P106 "Organic Chemical" @default.
- NCIT_C45873 NCIT_P107 "EF5" @default.
- NCIT_C45873 NCIT_P108 "EF5" @default.
- NCIT_C45873 NCIT_P175 "684681" @default.
- NCIT_C45873 NCIT_P207 "C0382334" @default.
- NCIT_C45873 NCIT_P210 "152721-37-4" @default.
- NCIT_C45873 NCIT_P319 "383HJ2T87O" @default.
- NCIT_C45873 NCIT_P322 "CTRP" @default.
- NCIT_C45873 NCIT_P322 "FDA" @default.
- NCIT_C45873 NCIT_P325 "A drug that is used to plan cancer treatment by measuring oxygen levels in tumor cells." @default.
- NCIT_C45873 NCIT_P329 "43025" @default.
- NCIT_C45873 NCIT_P330 "43025" @default.
- NCIT_C45873 NCIT_P366 "EF5" @default.
- NCIT_C45873 NCIT_P399 "43025" @default.
- NCIT_C45873 normalizedInformationContent "100" @default.
- NCIT_C45873 referenceCount "1" @default.
- NCIT_C45873 hasExactSynonym "2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) Acetamide" @default.
- NCIT_C45873 hasExactSynonym "EF-5" @default.
- NCIT_C45873 hasExactSynonym "EF5" @default.
- NCIT_C45873 inSubset NCIT_C116977 @default.
- NCIT_C45873 inSubset NCIT_C116978 @default.
- NCIT_C45873 inSubset NCIT_C176424 @default.
- NCIT_C45873 inSubset NCIT_C63923 @default.
- NCIT_C45873 type Class @default.
- NCIT_C45873 isDefinedBy ncit.owl @default.
- NCIT_C45873 label "EF5" @default.
- NCIT_C45873 subClassOf NCIT_C1908 @default.
- NCIT_C45873 subClassOf NCIT_C1913 @default.
- NCIT_C45873 subClassOf NCIT_C1937 @default.
- NCIT_C45873 subClassOf NCIT_C45678 @default.
- NCIT_C45873 subClassOf NCIT_C45873 @default.
- NCIT_C45873 subClassOf NCIT_C552 @default.
- NCIT_C45873 subClassOf NCIT_C554 @default.
- NCIT_C45873 subClassOf NCIT_C718 @default.
- NCIT_C45873 subClassOf NCIT_C802 @default.