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- NCIT_C45907 IAO_0000115 "The hydrochloride salt form of promethazine, a phenothiazine derivative with antihistaminic, sedative and antiemetic properties. Promethazine hydrochloride selectively blocks peripheral H1 receptors thereby diminishing the effects of histamine on effector cells. Promethazine hydrochloride also blocks the central histaminergic receptors, thereby depressing the reticular system causing sedative and hypnotic effects. In addition, promethazine hydrochloride also has centrally acting anticholinergic properties and probably mediates nausea and vomiting by acting on the medullary chemoreceptive trigger zone." @default.
- NCIT_C45907 NCIT_A6 NCIT_C779 @default.
- NCIT_C45907 NCIT_NHC0 "C45907" @default.
- NCIT_C45907 NCIT_P106 "Organic Chemical" @default.
- NCIT_C45907 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C45907 NCIT_P108 "Promethazine Hydrochloride" @default.
- NCIT_C45907 NCIT_P175 "231688" @default.
- NCIT_C45907 NCIT_P207 "C0546876" @default.
- NCIT_C45907 NCIT_P210 "58-33-3" @default.
- NCIT_C45907 NCIT_P319 "R61ZEH7I1I" @default.
- NCIT_C45907 NCIT_P322 "FDA" @default.
- NCIT_C45907 NCIT_P329 "39567" @default.
- NCIT_C45907 NCIT_P330 "39567" @default.
- NCIT_C45907 NCIT_P350 "C17H20N2S.HCl" @default.
- NCIT_C45907 NCIT_P366 "Promethazine_Hydrochloride" @default.
- NCIT_C45907 NCIT_P368 "CHEBI:8462" @default.
- NCIT_C45907 NCIT_P399 "39567" @default.
- NCIT_C45907 normalizedInformationContent "100" @default.
- NCIT_C45907 referenceCount "1" @default.
- NCIT_C45907 hasExactSynonym "Anergan" @default.
- NCIT_C45907 hasExactSynonym "N-(2-Dimethylaminopropyl-1)phenothiazine Hydrochloride" @default.
- NCIT_C45907 hasExactSynonym "PROMETHAZINE HYDROCHLORIDE" @default.
- NCIT_C45907 hasExactSynonym "Phencen" @default.
- NCIT_C45907 hasExactSynonym "Phenergan" @default.
- NCIT_C45907 hasExactSynonym "Prometh" @default.
- NCIT_C45907 hasExactSynonym "Promethazine HCl" @default.
- NCIT_C45907 hasExactSynonym "Promethazine Hydrochloride" @default.
- NCIT_C45907 hasExactSynonym "Prorex" @default.
- NCIT_C45907 hasExactSynonym "Provigan" @default.
- NCIT_C45907 hasExactSynonym "Remsed" @default.
- NCIT_C45907 hasExactSynonym "V-Gan" @default.
- NCIT_C45907 hasExactSynonym "Zipan-50" @default.
- NCIT_C45907 inSubset NCIT_C176424 @default.
- NCIT_C45907 inSubset NCIT_C63923 @default.
- NCIT_C45907 type Class @default.
- NCIT_C45907 isDefinedBy ncit.owl @default.
- NCIT_C45907 label "Promethazine Hydrochloride" @default.
- NCIT_C45907 subClassOf NCIT_C1908 @default.
- NCIT_C45907 subClassOf NCIT_C1909 @default.
- NCIT_C45907 subClassOf NCIT_C267 @default.
- NCIT_C45907 subClassOf NCIT_C29756 @default.
- NCIT_C45907 subClassOf NCIT_C45907 @default.
- NCIT_C45907 subClassOf NCIT_C740 @default.
- NCIT_C45907 subClassOf NCIT_C78272 @default.