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- NCIT_C47397 IAO_0000115 "A tricyclic antidepressant of the dibenzoxazepine class. Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. This drug is used to treat symptoms of depression and may cause tardive dyskinesia. Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side effects seen with this agent." @default.
- NCIT_C47397 NCIT_NHC0 "C47397" @default.
- NCIT_C47397 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47397 NCIT_P108 "Amoxapine" @default.
- NCIT_C47397 NCIT_P207 "C0700992" @default.
- NCIT_C47397 NCIT_P210 "14028-44-5" @default.
- NCIT_C47397 NCIT_P319 "R63VQ857OT" @default.
- NCIT_C47397 NCIT_P322 "FDA" @default.
- NCIT_C47397 NCIT_P350 "C17H16ClN3O" @default.
- NCIT_C47397 NCIT_P366 "Amoxapine" @default.
- NCIT_C47397 NCIT_P368 "CHEBI:2675" @default.
- NCIT_C47397 normalizedInformationContent "100" @default.
- NCIT_C47397 referenceCount "1" @default.
- NCIT_C47397 hasExactSynonym "AMOXAPINE" @default.
- NCIT_C47397 hasExactSynonym "Amoxapine" @default.
- NCIT_C47397 hasExactSynonym "Asendin" @default.
- NCIT_C47397 hasExactSynonym "Demolox" @default.
- NCIT_C47397 hasExactSynonym "Dibenz(b,f)(1,4)oxazepine, 2-Chloro-11-(1-piperazinyl)-" @default.
- NCIT_C47397 inSubset NCIT_C63923 @default.
- NCIT_C47397 type Class @default.
- NCIT_C47397 isDefinedBy ncit.owl @default.
- NCIT_C47397 label "Amoxapine" @default.
- NCIT_C47397 subClassOf NCIT_C1908 @default.
- NCIT_C47397 subClassOf NCIT_C1909 @default.
- NCIT_C47397 subClassOf NCIT_C265 @default.
- NCIT_C47397 subClassOf NCIT_C47397 @default.
- NCIT_C47397 subClassOf NCIT_C78272 @default.
- NCIT_C47397 subClassOf NCIT_C94727 @default.