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- NCIT_C47404 IAO_0000115 "The hydrochloride salt form of articaine, an amide-type local anesthetic. Articaine hydrochloride reversibly blocks nerve impulse conduction by binding to specific membrane sodium ion channels thereby interfering with the electrical excitation in the nerve, slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. This results in a loss of sensation at the injection site. Articaine hydrochloride is used for relief of pain in minor operations, usually in combination with the vasoconstrictor epinephrine." @default.
- NCIT_C47404 NCIT_A6 NCIT_C72173 @default.
- NCIT_C47404 NCIT_NHC0 "C47404" @default.
- NCIT_C47404 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47404 NCIT_P108 "Articaine Hydrochloride" @default.
- NCIT_C47404 NCIT_P207 "C0007300" @default.
- NCIT_C47404 NCIT_P210 "23964-57-0" @default.
- NCIT_C47404 NCIT_P319 "QS9014Q792" @default.
- NCIT_C47404 NCIT_P322 "FDA" @default.
- NCIT_C47404 NCIT_P350 "C13H20N2O3S.ClH" @default.
- NCIT_C47404 NCIT_P366 "Articaine_Hydrochloride" @default.
- NCIT_C47404 normalizedInformationContent "100" @default.
- NCIT_C47404 referenceCount "1" @default.
- NCIT_C47404 hasExactSynonym "2-Thiophenecarboxylic Acid, 4-Methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, Methyl Ester, Monohydrochloride" @default.
- NCIT_C47404 hasExactSynonym "4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic Acid Methyl Ester HCl" @default.
- NCIT_C47404 hasExactSynonym "ARTICAINE HYDROCHLORIDE" @default.
- NCIT_C47404 hasExactSynonym "Articaine Hydrochloride" @default.
- NCIT_C47404 hasExactSynonym "Septanest" @default.
- NCIT_C47404 hasExactSynonym "Septocaine" @default.
- NCIT_C47404 hasExactSynonym "Ultracaine" @default.
- NCIT_C47404 inSubset NCIT_C63923 @default.
- NCIT_C47404 type Class @default.
- NCIT_C47404 isDefinedBy ncit.owl @default.
- NCIT_C47404 label "Articaine Hydrochloride" @default.
- NCIT_C47404 subClassOf NCIT_C1908 @default.
- NCIT_C47404 subClassOf NCIT_C1909 @default.
- NCIT_C47404 subClassOf NCIT_C245 @default.
- NCIT_C47404 subClassOf NCIT_C47404 @default.
- NCIT_C47404 subClassOf NCIT_C78272 @default.