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- NCIT_C47414 IAO_0000115 "A synthetic prostamide and structural prostaglandin analogue with ocular hypotensive activity. Bimatoprost mimics the effects of the endogenous prostamides and reduces intraocular pressure by increasing outflow of aqueous humor through both the pressure-sensitive outflow pathway (the trabecular meshwork), and the pressure-insensitive outflow pathway (the uveoscleral routes). It is not clear whether bimatoprost lowers intraocular pressure by stimulating F-Prostanoid receptors or by acting on specific prostamide receptors." @default.
- NCIT_C47414 NCIT_NHC0 "C47414" @default.
- NCIT_C47414 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47414 NCIT_P108 "Bimatoprost" @default.
- NCIT_C47414 NCIT_P207 "C0937917" @default.
- NCIT_C47414 NCIT_P210 "155206-00-1" @default.
- NCIT_C47414 NCIT_P302 "Hypotrichosis of Eyelashes" @default.
- NCIT_C47414 NCIT_P319 "QXS94885MZ" @default.
- NCIT_C47414 NCIT_P322 "FDA" @default.
- NCIT_C47414 NCIT_P325 "A drug used under the name Latisse to increase the length, thickness, and darkness of eyelashes. It is being studied as a way to increase the growth of eyelashes and eyebrows in patients given chemotherapy for cancer. Bimatoprost is also used under the name Lumigan to treat glaucoma (a build-up of fluid in the eye). It lowers pressure in the eye by increasing the flow of natural eye fluids out of the eye. It is a type of prostaglandin analog." @default.
- NCIT_C47414 NCIT_P350 "C25H37NO4" @default.
- NCIT_C47414 NCIT_P366 "Bimatoprost" @default.
- NCIT_C47414 NCIT_P368 "CHEBI:51230" @default.
- NCIT_C47414 normalizedInformationContent "100" @default.
- NCIT_C47414 referenceCount "1" @default.
- NCIT_C47414 hasExactSynonym "5-Heptenamide, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-,(5Z)-" @default.
- NCIT_C47414 hasExactSynonym "AGN 192024" @default.
- NCIT_C47414 hasExactSynonym "BIMATOPROST" @default.
- NCIT_C47414 hasExactSynonym "Bimatoprost" @default.
- NCIT_C47414 hasExactSynonym "Latisse" @default.
- NCIT_C47414 hasExactSynonym "Lumigan" @default.
- NCIT_C47414 hasExactSynonym "bimatoprost" @default.
- NCIT_C47414 inSubset NCIT_C63923 @default.
- NCIT_C47414 type Class @default.
- NCIT_C47414 isDefinedBy ncit.owl @default.
- NCIT_C47414 label "Bimatoprost" @default.
- NCIT_C47414 subClassOf NCIT_C1908 @default.
- NCIT_C47414 subClassOf NCIT_C1909 @default.
- NCIT_C47414 subClassOf NCIT_C29705 @default.
- NCIT_C47414 subClassOf NCIT_C47414 @default.
- NCIT_C47414 subClassOf NCIT_C78283 @default.
- NCIT_C47414 subClassOf NCIT_C78568 @default.