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- NCIT_C47415 IAO_0000115 "A 20 amino acid long synthetic peptide with thrombin-specific anticoagulant properties. Bivalirudin reversibly binds thrombin, free as well as clot bound, at the catalytic site and the anion-binding exosite, thereby preventing the formation and activation of fibrin, factor XIIIa, and other coagulation factors. This drug is primarily used during coronary angioplasty procedures, in combination with aspirin, in patients with unstable angina." @default.
- NCIT_C47415 NCIT_A5 NCIT_C142963 @default.
- NCIT_C47415 NCIT_NHC0 "C47415" @default.
- NCIT_C47415 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C47415 NCIT_P108 "Bivalirudin" @default.
- NCIT_C47415 NCIT_P207 "C0168273" @default.
- NCIT_C47415 NCIT_P210 "128270-60-0" @default.
- NCIT_C47415 NCIT_P319 "TN9BEX005G" @default.
- NCIT_C47415 NCIT_P322 "ACC/AHA" @default.
- NCIT_C47415 NCIT_P322 "FDA" @default.
- NCIT_C47415 NCIT_P325 "Bivalirudin is a semisynthetic derivative of hirudin and is a highly specific inhibitor of thrombin." @default.
- NCIT_C47415 NCIT_P350 "C98H138N24O33" @default.
- NCIT_C47415 NCIT_P366 "Bivalirudin" @default.
- NCIT_C47415 NCIT_P368 "CHEBI:59173" @default.
- NCIT_C47415 normalizedInformationContent "100" @default.
- NCIT_C47415 referenceCount "1" @default.
- NCIT_C47415 hasExactSynonym "BIVALIRUDIN" @default.
- NCIT_C47415 hasExactSynonym "Bivalirudin" @default.
- NCIT_C47415 hasExactSynonym "Hirulog" @default.
- NCIT_C47415 hasExactSynonym "L-Leucine, D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-" @default.
- NCIT_C47415 inSubset NCIT_C173381 @default.
- NCIT_C47415 inSubset NCIT_C173383 @default.
- NCIT_C47415 inSubset NCIT_C191200 @default.
- NCIT_C47415 inSubset NCIT_C191387 @default.
- NCIT_C47415 inSubset NCIT_C191406 @default.
- NCIT_C47415 inSubset NCIT_C191671 @default.
- NCIT_C47415 inSubset NCIT_C63923 @default.
- NCIT_C47415 type Class @default.
- NCIT_C47415 isDefinedBy ncit.owl @default.
- NCIT_C47415 label "Bivalirudin" @default.
- NCIT_C47415 subClassOf NCIT_C173066 @default.
- NCIT_C47415 subClassOf NCIT_C1908 @default.
- NCIT_C47415 subClassOf NCIT_C1909 @default.
- NCIT_C47415 subClassOf NCIT_C263 @default.
- NCIT_C47415 subClassOf NCIT_C47415 @default.
- NCIT_C47415 subClassOf NCIT_C78275 @default.